PMID: 11907150Mar 22, 2002Paper

Pharmacology and toxicology of astrocyte-neuron glutamate transport and cycling

The Journal of Pharmacology and Experimental Therapeutics
Ursula SonnewaldMichael Aschner

Abstract

The interaction between astrocytes and neurons is examined from the standpoint of glutamate neurotoxicity. The review details 1. the distribution of glutamate transporters on astrocytes and neurons, provoking a reformulation of the interdependence between these two cell types in removing extracellular glutamate and preventing excitotoxic injury; 2. the potential involvement of aberrant glutamate transporter function in the etiology of neuropathological conditions; 3. the role of astrocyte-neuron interaction in widely divergent aspects of brain energetics; 4. the role of astrocytes in the process of glutamate recycling within the context of anesthetic treatment with pentobarbital and thiopental.

References

Nov 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·T StorckW Stoffel
May 28, 1992·The New England Journal of Medicine·J D RothsteinR W Kuncl
Nov 1, 1992·Journal of Neurobiology·D W Choi
Jul 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·V L DawsonS H Snyder
Nov 1, 1990·Trends in Pharmacological Sciences·D Nicholls, D Attwell
Dec 1, 1985·Biulleten' eksperimental'noĭ biologii i meditsiny·V A Khazanov, A S Saratikov
Nov 19, 1984·FEBS Letters·A PastuszkoM Erecińska
Sep 1, 1995·Neuron·J I WadicheM P Kavanaugh
Jul 1, 1995·Annals of Neurology·J D RothsteinR W Kuncl
Jul 14, 1995·The Journal of Biological Chemistry·Y KanaiM A Hediger
Aug 5, 1993·Nature·M Lafon-CazalJ Bockaert
Sep 1, 1994·Neuron·J D RothsteinR W Kuncl
Jun 1, 1994·Current Opinion in Neurobiology·D Attwell, P Mobbs
Oct 25, 1994·Proceedings of the National Academy of Sciences of the United States of America·L Pellerin, P J Magistretti
Sep 1, 1993·Neuron·D AttwellM Szatkowski
Jan 1, 1996·Journal of Neurochemistry·M C McKennaH R Zielke
Apr 30, 1996·Proceedings of the National Academy of Sciences of the United States of America·S Eliasof, C E Jahr
Oct 17, 1996·Nature·N Zerangue, M P Kavanaugh
Sep 1, 1996·Neurochemical Research·U SonnewaldA Schousboe
Apr 15, 1997·Proceedings of the National Academy of Sciences of the United States of America·J L ArrizaS G Amara
Sep 23, 1997·Glia·U SonnewaldA Schousboe
Mar 21, 1998·Brain Research·N ZarchinA Mayevsky
Sep 30, 1998·The European Journal of Neuroscience·K WataseK Tanaka
Oct 21, 1998·Developmental Neuroscience·L PellerinP J Magistretti
Oct 21, 1998·Developmental Neuroscience·A HåbergU Sonnewald
Apr 21, 1999·Epilepsy Research·C D FerrieR O Robinson

❮ Previous
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Citations

Dec 26, 2006·Medical Molecular Morphology·Yoshinori FujimuraKen Haruma
Oct 31, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Zhan LiuZhiqiang Su
Jun 5, 2003·Neurotoxicology·Kent E VranaMichael Aschner
Jul 18, 2002·Nature Reviews. Drug Discovery·Daniela SalveminiSalvatore Cuzzocrea
Nov 26, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Flemming ToftengFin Stolze Larsen
May 9, 2013·Doklady Biological Sciences : Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections·M Yu IniouchineA B Vol'nova
Oct 9, 2003·Clinical Pharmacokinetics·Stanley S Davis, Lisbeth Illum
May 1, 2010·Reproduction : the Official Journal of the Society for the Study of Fertility·James A MacLean, Miles F Wilkinson
Apr 21, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Guido VerhoevenKarel De Gendt
Jun 12, 2009·Human Reproduction Update·Katrien StouffsWilly Lissens
May 15, 2007·Journal of the Neurological Sciences·Cláudia FunchalMoacir Wajner
Jan 3, 2014·Journal of Neurochemistry·Silvina TallisJuan C Perazzo
Apr 9, 2013·Journal of Magnetic Resonance Imaging : JMRI·Sven HädelFlorian Schubert
Jun 15, 2004·Progress in Neurobiology·Kiyoshi MorimotoRonald J Racine
Mar 15, 2006·Brain Research Reviews·David A Aremu, Shunsuke Meshitsuka
Jun 4, 2015·Channels·Claudia KarusChristine R Rose
Jun 20, 2008·Schizophrenia Research·Amy E SteffekJames H Meador-Woodruff
Dec 14, 2011·Molecular and Cellular Neurosciences·Cynthia L Bethea, Arubala P Reddy
Sep 26, 2006·NMR in Biomedicine·Isidro Bonilla, Richard E Snyder
Feb 24, 2006·Journal of Neuroscience Research·Virginia G BarrosMarta C Antonelli
Oct 22, 2002·The Journal of Pharmacology and Experimental Therapeutics·S CarnesecchiF Raul
May 4, 2010·Metabolic Brain Disease·André Quincozes-SantosCarlos Alberto Gonçalves
Feb 6, 2017·Journal of Neuroscience Research·Niklas J GerkauChristine R Rose
Apr 16, 2002·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Maohe YanJeffrey L Blumer

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