PMID: 18193805Jun 1, 1992Paper

Pharmacology of beta blockers

Srpski arhiv za celokupno lekarstvo
T Kazić

Abstract

Beta blockers possess several pharmacologic characteristics which highly recommend them for use in the therapeutic branches of medicine: their actions are mild and develop slowly, providing thus a fine regulation of cardiovascular functions; no tolerance occurs to the pharmacodynamic actions of beta blockers, and therefore they ean be used for years without loss of activity; pharmacokinetics of beta blockers is adjusted to the current therapeutic needs by molecular manipulation and/or pharmaceutical technology, and nowadays many members of this group may be used 1-2 times daily which is optimal dosage schedule for chronic diseases. Due to the convenient pharmacologic profile, beta blockers are widely used in clinical medicine, first of all in cardiology for the treatment of hypertension, ischaemic heart disease, cardiac arrhythmias, in acute myocardial infarction and its primary and secondary prevention, and, to a lesser degree, in ophthalmology, neurology, psychiatry and other branches of medicine.

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