PMID: 9547758Apr 21, 1998Paper

Pharmacology of drug transfer across the placenta

Obstetrics and Gynecology Clinics of North America
M Garland

Abstract

The effect of drugs in the fetus can be thought of in terms of the dose-response based on a knowledge of the general principles by which drug is transferred from the mother to the fetus. Fetal drug concentration, which determines the fetal response, is a function of the maternal concentration, the placental permeability, the fetal drug clearance, and differences in protein binding and ionization between the maternal and fetal plasma.

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Citations

Jul 17, 2013·Paediatric Drugs·Jana DekremFrédéric Amant
Mar 17, 2007·SAR and QSAR in Environmental Research·M HewittM T D Cronin
Dec 29, 1998·Journal of Women's Health
Feb 28, 2002·Clinical Obstetrics and Gynecology·Gerald G Briggs
Jan 8, 2000·Plastic and Reconstructive Surgery·G P Hetter
Feb 15, 2001·Plastic and Reconstructive Surgery·P E ButlerM J Yaremchuk
Dec 22, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·M GarlandR I Stark
Dec 25, 2004·Obstetrical & Gynecological Survey·P J van Runnard HeimelH W Bruinse
Oct 30, 2013·Plastic and Reconstructive Surgery·Cemile Nurdan OzturkJames E Zins
Jun 2, 2004·Clinical Pharmacokinetics·Michael R SymeJeffrey A Keelan
Apr 6, 2006·Clinical Pharmacokinetics·Shing-Shun N SiuTze-Kin Lau
Oct 29, 2013·Annual Review of Pharmacology and Toxicology·Fatma EtwelGideon Koren
Mar 10, 2016·Neurotoxicology·Dorothée C-M VercruysseFrederic Amant
Mar 8, 2011·Birth Defects Research. Part A, Clinical and Molecular Teratology·Lyn ColvinCarol Bower
Jul 26, 2006·Expert Opinion on Drug Metabolism & Toxicology·Denis EvseenkoJeffrey A Keelan
May 6, 2016·Journal of Thrombosis and Haemostasis : JTH·P BapatS Ito
Oct 12, 2016·Scientific Reports·Jerrie S RefuerzoBiana Godin
Sep 1, 2005·Pediatric Cardiology·V V DimasK E Ward
Jan 7, 2006·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·N Y Schürer, L Wiest
May 1, 2001·Current Protocols in Pharmacology·M Williams
Sep 11, 2019·Journal of Clinical Pharmacology·André DallmannJohn van den Anker
Dec 19, 2003·Expert Opinion on Drug Safety·L A Magee, S Abdullah
Oct 21, 2004·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Marianne GarlandRaymond I Stark
Jan 31, 2006·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Marianne GarlandRaymond I Stark
May 26, 2004·Pediatric Clinics of North America·Enrique M OstreaMaria Asuncion Silvestre
Sep 12, 2018·Neonatology·Sota IwataniDavid K Stevenson
Nov 5, 2005·Journal de gynécologie, obstétrique et biologie de la reproduction·L-J SalomonC-A Cuénod

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