PMID: 3762195Jul 1, 1986Paper

Pharmacology of lemongrass (Cymbopogon citratus Stapf). I. Effects of teas prepared from the leaves on laboratory animals

Journal of Ethnopharmacology
E A CarliniO F Bueno

Abstract

Cymbopogon citratus is one of the most used plants in Brazilian folk medicine for the treatment of nervous and gastrointestinal disturbances. It is also used in many other places to treat feverish conditions. The usual way to use it is by ingesting an infusion made by pouring boiling water on fresh or dried leaves (which is called "abafado" in Portuguese). Abafados obtained from lemongrass harvested in three different areas of Brazil (Ceará, Minas Gerais and São Paulo States) were tested on rats and mice in an attempt to add experimental confirmation to its popular medicinal use. Citral, the main constituent of the essential oil in Brazilian lemongrass, was also studied for comparison. Oral doses of abafados up to 40 times (C40) larger than the corresponding dosage taken by humans, or of 200 mg/kg of citral, were unable to decrease body temperature of normal rats and/or rats made hyperthermic by previous administration of pyrogen. However, both compounds acted when injected by intraperitoneal route. Oral administration of doses C20 -C100 of abafados and 200 mg/kg of citral did not change the intestinal transit of a charcoal meal in mice, nor did it decrease the defecation scores of rats in an open-field arena. Again, by intrape...Continue Reading

References

Jan 1, 1978·Pharmacology·J M Cunha, J Masur
Nov 1, 1975·Pharmacology, Biochemistry, and Behavior·J M Monti, E A Carlini
Aug 1, 1978·Epilepsia·R L KrallE A Swinyard
Jan 1, 1976·Pharmacology·A B Sell, E A Carlini
Jan 1, 1971·Psychopharmacologia·B P Poschel
Jan 1, 1983·Journal of Ethnopharmacology·P G Xaio
Jun 1, 1981·Experientia·E A CarliniJ L Zelger
Nov 1, 1958·The Journal of Pharmacy and Pharmacology·H RILEY, A SPINKS

❮ Previous
Next ❯

Citations

Aug 21, 2013·In Vitro Cellular & Developmental Biology. Animal·Ghazaleh S TayeboonS Nasser Ostad
Sep 1, 1993·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·I F DelgadoF J Paumgartten
Jan 1, 1993·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·I F DelgadoF J Paumgartten
Feb 6, 1995·Toxicology·A C NogueiraF J Paumgartten
Feb 1, 1989·Journal of Ethnopharmacology·D CarbajalZ Tolon
Jul 1, 1991·Journal of Ethnopharmacology·M M BernardiR Giorgi
Aug 1, 1991·Journal of Ethnopharmacology·B B LorenzettiS H Ferreira
Jan 1, 1995·Journal of Ethnopharmacology·M J BatatinhaM M Bernardi
Apr 9, 2005·Journal of Ethnopharmacology·C I F FrancoA R Antoniolli
Aug 28, 1998·Journal of Ethnopharmacology·L C MoraisR N Almeida
Jun 6, 2000·Journal of Ethnopharmacology·G S VianaF J Matos
Aug 8, 2009·Natural Product Research·J M SforcinJ K Bastos
Apr 13, 2011·Journal of Medicinal Food·Lucindo Quintans-JúniorDaniel Pens Gelain
Aug 2, 2006·Biological & Pharmaceutical Bulletin·Hiroyuki SakakibaraJunji Terao
Jan 8, 2008·Bioscience, Biotechnology, and Biochemistry·Hiroyuki SakakibaraJunji Terao
May 3, 2014·BioMed Research International·Mohammed F Halabi, Bassem Y Sheikh
Oct 19, 2005·Journal of Ethnopharmacology·Adriana R CamposVietla S N Rao
Oct 15, 2008·Neurochemical Research·Romaiana Picada PereiraJoão Batista Teixeira Rocha
Nov 23, 2011·Journal of Smooth Muscle Research = Nihon Heikatsukin Gakkai Kikanshi·Ramachandran Chitra DeviRosnah Ismail
Aug 25, 2015·Journal of Ethnopharmacology·Tânia M Antonelli-UshirobiraJoão C P de Mello
Sep 27, 2015·BMC Complementary and Alternative Medicine·Abdul MannanRashidur Rahman
Sep 16, 2015·Journal of Ethnobiology and Ethnomedicine·Y N ClementC E Seaforth
Jun 8, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·R Chitra DeviR Ismail
Jul 22, 2011·Journal of Biomedicine & Biotechnology·Vanine Gomes MotaJacicarlos Lima de Alencar
Jul 15, 2015·Journal of Ethnopharmacology·Joana SagradasMaria Teresa Batista
Feb 14, 2012·Journal of Ethnopharmacology·Mohd Sajjad Ahmad Khan, Iqbal Ahmad
Jul 20, 2011·Journal of Ethnopharmacology·Celso A Rodrigues de Almeida CostaMirtes Costa
Jun 14, 2000·Seizure : the Journal of the British Epilepsy Association·W M NsourI C Wong
Jun 23, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Celso A R A CostaMirtes Costa
Apr 27, 2005·Phytotherapy Research : PTR·R N AlmeidaJ M Barbosa-Filho
Aug 12, 1998·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·F J PaumgarttenI Chahoud
Mar 3, 2005·Journal of Pharmaceutical and Biomedical Analysis·Cristiane da S RauberElfrides E S Schapoval
Mar 9, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sharlene Lopes PereiraGisele Zapata-Sudo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here