Jan 1, 1976

Pharmacology of methvin--a new ganglionic blocking preparation of short-term effect

Farmakologiia i toksikologiia
A A Vakhabov

Abstract

Methvin (vincanin chlormethylate) is an active ganglion blocking agent of a short-term action. As regards its gangliolytic action it is approximately 6 times superior to afronad. In test animals the drug produces a well-marked and short-term (easily controllable) hypotensive effect, without causing any histamine-like and direct vasodilation action. When used in relatively high doses methvin blocks the neuro-muscular conduction, potentiates the action of major muscle relaxants. A study of methvin in clinical conditions confirmed its high gangliolytic activity previously revealed in experiments.

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Mentioned in this Paper

Histamine Measurement
Diastolic Blood Pressure
Muscle relaxants FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
Hypotensive
Ganglia
Muscle relaxants
Muscle
Allergy Testing Histamine (Lab Test)
Vasodilation [PE]
Histamine

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