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Pharmacotherapy: concepts of pathogenesis and emerging treatments. Optimising the strategy of care in early rheumatoid arthritis

Best Practice & Research. Clinical Rheumatology

Aug 25, 2010

James Dale, Duncan Porter

Abstract

In rheumatoid arthritis (RA), early use of disease-modifying anti-rheumatic drugs (DMARDs), intensive follow-up and 'treating to target' to achieve low disease activity produce significant improvements in measures of disease activity, functional impairment and retard erosive radiographi...read more

Mentioned in this Paper

Leflunomide
Immune Response
Pathogenic Aspects
Biochemical Pathway
Autoantibodies
Meta-Analysis (Publications)
Antirheumatic Drugs, Disease-Modifying
Pathogenesis
Gait, Drop Foot
Tumor Necrosis Factor-alpha
28
Paper Details
References
  • References54
  • Citations7
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  • References54
  • Citations7
1

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Pharmacotherapy: concepts of pathogenesis and emerging treatments. Optimising the strategy of care in early rheumatoid arthritis

Best Practice & Research. Clinical Rheumatology

Aug 25, 2010

James Dale, Duncan Porter

PMID: 20732643

DOI: 10.1016/j.berh.2009.11.009

Abstract

In rheumatoid arthritis (RA), early use of disease-modifying anti-rheumatic drugs (DMARDs), intensive follow-up and 'treating to target' to achieve low disease activity produce significant improvements in measures of disease activity, functional impairment and retard erosive radiographi...read more

Mentioned in this Paper

Leflunomide
Immune Response
Pathogenic Aspects
Biochemical Pathway
Autoantibodies
Meta-Analysis (Publications)
Antirheumatic Drugs, Disease-Modifying
Pathogenesis
Gait, Drop Foot
Tumor Necrosis Factor-alpha
28

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Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Chemokines & Chemokine Receptors

Chemokines are a subset of cytokines which induce chemotaxis in cells expressing chemokine receptors. Chemokines can be broadly categorized into two functional subgroups, homeostatic (basal expression in lymphoid tissues for surveillance purposes) or inflammatory (released during injury to recruit immune effector cells). Chemokine receptors are G-protein coupled receptors which, upon chemokine binding, induce calcium influx into the cell. Find the latest research on chemokines and chemokine receptors here.

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Paper Details
References
  • References54
  • Citations7
12345...
  • References54
  • Citations7
1
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