Pharmacotherapy for hypertension in adults 60 years or older.

The Cochrane Database of Systematic Reviews
Vijaya M MusiniJames M Wright

Abstract

This is the second substantive update of this review. It was originally published in 1998 and was previously updated in 2009. Elevated blood pressure (known as 'hypertension') increases with age - most rapidly over age 60. Systolic hypertension is more strongly associated with cardiovascular disease than is diastolic hypertension, and it occurs more commonly in older people. It is important to know the benefits and harms of antihypertensive treatment for hypertension in this age group, as well as separately for people 60 to 79 years old and people 80 years or older. Primary objective• To quantify the effects of antihypertensive drug treatment as compared with placebo or no treatment on all-cause mortality in people 60 years and older with mild to moderate systolic or diastolic hypertensionSecondary objectives• To quantify the effects of antihypertensive drug treatment as compared with placebo or no treatment on cardiovascular-specific morbidity and mortality in people 60 years and older with mild to moderate systolic or diastolic hypertension• To quantify the rate of withdrawal due to adverse effects of antihypertensive drug treatment as compared with placebo or no treatment in people 60 years and older with mild to moderate sy...Continue Reading

References

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Citations

Sep 6, 2019·Drug and Therapeutics Bulletin·James A Cave
Jun 11, 2020·The Cochrane Database of Systematic Reviews·Emily ReeveDanijela Gnjidic
Apr 23, 2020·Frontiers in Cardiovascular Medicine·Michel BurnierGregoire Wuerzner
Dec 18, 2020·The Cochrane Database of Systematic Reviews·Jose Agustin ArguedasJames M Wright
Feb 26, 2021·The Cochrane Database of Systematic Reviews·Ling-Ling LeeHui-Hsin Lin
Dec 6, 2021·Age and Ageing·Jane A H MasoliChakravarthi Rajkumar

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