Pharmacotherapy for stress urinary incontinence : present and future options

Drugs
Norman R ZinnerLars Viktrup

Abstract

Stress urinary incontinence (SUI) is the accidental leakage of urine associated with physical activities such as running, jumping or lifting, or with sneezing and coughing. Worldwide, SUI is a highly prevalent condition, both in young and elderly women, and is a condition fraught with social isolation, loss of self-esteem and significant financial burden. Most women with SUI assume that it is an inevitable part of aging and "suffer in silence", relying on absorbent pads or lifestyle changes to cope with their condition.Unfortunately, for those who do seek medical treatment, the absence of effective and well tolerated pharmacological treatments for SUI limits the clinician's choices to behavioural modification, biofeedback and surgery. Many of the nonsurgical approaches have low success rates, particularly in the elderly and more severely afflicted. Although most continence surgeries have been reported to produce very high cure rates, many women are willing to live with their condition rather than undergo such invasive options. In an attempt to help these patients, some physicians prescribe off-label agents, including tricyclic antidepressants such as imipramine, alpha- and beta-adrenoceptor agonists, and estrogen replacement th...Continue Reading

References

Dec 1, 1994·Maturitas·C J Sultana, M D Walters
Oct 1, 1996·British Journal of Urology·N A Black, S H Downs
Jan 28, 1999·Obstetrics and Gynecology Clinics of North America·R C Bump, P A Norton
Dec 16, 2000·The New England Journal of Medicine·G A Fleming
May 24, 2001·The New England Journal of Medicine·J C Bailar
Aug 20, 2002·Psychopharmacology·Catherine J HarmerGuy M Goodwin
Sep 23, 2003·The Journal of Urology·Roger R DmochowskiUNKNOWN Duloxetine Urinary Incontinence Study Group
Feb 14, 2004·BJOG : an International Journal of Obstetrics and Gynaecology·Philip van KerrebroeckUNKNOWN Duloxetine Urinary Incontinence Study Group
May 25, 2004·Primary Care Companion to the Journal of Clinical Psychiatry·Craig H. MallinckrodtPierre V. Tran

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Citations

Jan 9, 2007·International Urogynecology Journal and Pelvic Floor Dysfunction·Heinz R Augsburger, Marianne Oswald
Jun 19, 2012·European Journal of Clinical Pharmacology·Gianluca TrifiròFabio Samani
Jul 16, 2005·The Nurse Practitioner·Mikel Gray
May 17, 2011·Indian Journal of Pharmacology·P DeepakT K Sen
Jun 15, 2013·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Donald NeffR Corey O'Connor
Jun 2, 2005·Current Opinion in Urology·David Castro-Diaz, Maria Antonia Pascual Amoros
Oct 28, 2015·International Journal of Urology : Official Journal of the Japanese Urological Association·Saori NishijimaHideyuki Yamamoto
May 24, 2011·Urology·Argimiro Collado SerraEduardo Solsona Narbón
Nov 5, 2008·Pharmacoepidemiology and Drug Safety·Helga GardarsdottirEibert R Heerdink
Jun 17, 2014·International Journal of Urology : Official Journal of the Japanese Urological Association·Kimio SugayaSaori Nishijima
Sep 8, 2006·Journal of Affective Disorders·H GardarsdottirA C G Egberts
Feb 10, 2007·Current Medical Research and Opinion·Rodney A Appell, G Willy Davila
Apr 16, 2015·Korean journal of urology·Ha Bum JungSung Tae Cho
Jul 21, 2020·American Journal of Physiology. Renal Physiology·Jun YangMargot S Damaser
Mar 4, 2009·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Pradeep TyagiMichael B Chancellor

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