Pharmacotherapy Pearls in Rheumatology for the Care of Older Adult Patients: Focus on Oral Disease-Modifying Antirheumatic Drugs and the Newest Small Molecule Inhibitors

Rheumatic Diseases Clinics of North America
Blas Y BetancourtAnanta Subedi

Abstract

Providing safe and effective pharmacotherapy to geriatric patients with rheumatologic disorders is challenging. Multidisciplinary care involving rheumatologists, primary care physicians, and other specialties can optimize benefit and reduce adverse outcomes. Oral disease-modifying antirheumatic drugs, including methotrexate, hydroxychloroquine, sulfasalazine, and leflunomide, and the small molecule inhibitors tofacitinib and apremilast have distinctive monitoring requirements and specific adverse reaction profiles. This article provides clinically relevant pearls for use of these interventions in older patients.

Citations

Jul 16, 2020·Phytotherapy Research : PTR·Haroon KhanSyed M M Shah
Jun 30, 2019·Drugs & Aging·Francesco CasoLuisa Costa
Apr 6, 2021·Journal of Gastroenterology and Hepatology·Astrid-Jane Williams
Jun 12, 2021·Zeitschrift für Gerontologie und Geriatrie·Ilke Coskun Benlidayi, Yesim Gokce Kutsal

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