PMID: 44122Sep 1, 1979

Pharmacotoxic psychoses in patients with neurological disorders during old age (author's transl)

Aktuelle Gerontologie
W Danielczyk


23.3 per cent out of 180 old patients (age above 60 years, 71 y in the mean) suffering from chronic cerebral disorders (3 large groups of disease) developed pharmacotoxic psychoses. This relative high percentage can be explained by psychotoxic side effects of the modern antiparkinson-therapy. The incidence to psychotoxicity of combined L-Dopa seems to be less marked in patients without Parkinson's disease when compared to patients with progredient nigrostriatal degeneration. Toxic delirium as a result of treatment with antidepressants, diuretics and digitalis was observable only in a few percentage. This occurance was even less pronounced in comparison to acute developing exogene psychoses in the same group of patients when drugs were not administered.

Related Concepts

Antipsychotic Effect
Abnormal Degeneration
Chronic Disease
Nerve Degeneration
Digitalis preparation
Antiparkinson Agents
Psychoses, Drug
Digitalis Glycosides
Diuretic Effect

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