Pharmacy effect on adherence to antidiabetic medications

Medical Care
Krishna P Sharma, Thomas N Taylor

Abstract

There have been a number of studies relating medication adherence to patient characteristics. There is less research on influence of health care providers on patients' medication-taking behavior. To evaluate the pharmacy-level effect on medication adherence for patients receiving antidiabetic medications. This was a hypothesis-driven retrospective study using cross-sectional design and insurance claims data. The main analytical interest was the pharmacy-level effect on proportion of days covered as the measure of medication adherence. Multilevel random and mixed-effect models were used to tease out the pharmacy-level effect on patient outcomes. The study population consisted individuals aged 18-64 years, insured under employer-sponsored private health plans. We estimated models with and without covariates. In both models, pharmacy cluster effect was statistically significant (P<0.001). In the model without covariates, pharmacy cluster effect accounted for 12.8% (95% confidence interval, 12.4%-13.1%) of total variance in adherence, whereas in the model with covariates pharmacies accounted for 12.1% (95% confidence interval, 11.6%-12.4%) of total variance. Covariates associated significantly with adherence were age, sex, mail ord...Continue Reading

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Citations

Dec 30, 2014·Journal of the American Pharmacists Association : JAPhA·Jun WuVirginia Noxon
Nov 5, 2013·Journal of the American Pharmacists Association : JAPhA·David A Holdford, Timothy J Inocencio
Apr 29, 2016·Journal of Managed Care & Specialty Pharmacy·Reethi N IyengarRebecca M Rabbitt
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Oct 2, 2020·Journal of General Internal Medicine·Bharathi RamachandranJulie A Schmittdiel
Oct 30, 2020·International Journal of Molecular Sciences·Ju-Ryoung Kim, Hyun Ah Kim

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