PharmGKB: A worldwide resource for pharmacogenomic information

Wiley Interdisciplinary Reviews. Systems Biology and Medicine
Julia M BarbarinoTeri E Klein

Abstract

As precision medicine becomes increasingly relevant in healthcare, the field of pharmacogenomics (PGx) also continues to gain prominence in the clinical setting. Leading institutions have begun to implement PGx testing and the amount of published PGx literature increases yearly. The Pharmacogenomics Knowledgebase (PharmGKB; www.pharmgkb.org) is one of the foremost worldwide resources for PGx knowledge, and the organization has been adapting and refocusing its mission along with the current revolution in genomic medicine. The PharmGKB website provides a diverse array of PGx information, from annotations of the primary literature to guidelines for adjusting drug treatment based on genetic information. It is freely available and accessible to everyone from researchers to clinicians to everyday citizens. PharmGKB was found over 17 years ago, but continues to be a vital resource for the entire PGx community and the general public. This article is categorized under: Translational, Genomic, and Systems Medicine > Translational Medicine.

References

Jan 15, 2003·Annual Review of Medicine·R NagasubramanianM J Ratain
Sep 5, 2006·Annual Review of Genomics and Human Genetics·Richard M Weinshilboum, Liewei Wang
Feb 7, 2008·Clinical Pharmacology and Therapeutics·J J SwenV H M Deneer
Dec 3, 2009·Pharmacogenetics and Genomics·Gianluigi ZazaRuss B Altman
Feb 16, 2010·Pharmacogenetics and Genomics·Liewei WangTeri E Klein
Mar 31, 2010·Pharmacogenomics·Caroline F ThornRuss B Altman
Jun 29, 2010·Thyroid : Official Journal of the American Thyroid Association·Colin J D RossUNKNOWN CPNDS Consortium
Jan 29, 2011·Clinical Pharmacology and Therapeutics·M V Relling, T E Klein
Jan 29, 2011·Clinical Pharmacology and Therapeutics·M V RellingUNKNOWN Clinical Pharmacogenetics Implementation Consortium
Mar 18, 2011·Clinical Pharmacology and Therapeutics·J J SwenH-J Guchelaar
Nov 19, 2011·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Stuart A Scott
May 31, 2012·Proceedings of the National Academy of Sciences of the United States of America·David A OstrovBjoern Peters
Jun 23, 2012·Nature·Patricia T IllingJames McCluskey
Jan 10, 2013·PLoS Computational Biology·Konrad J KarczewskiRuss B Altman
Apr 11, 2013·JAMA : the Journal of the American Medical Association·Denise M GoodmanEdward H Livingston
Feb 25, 2014·Clinical Pharmacology and Therapeutics·M A MartinUNKNOWN Clinical Pharmacogenetics Implementation Consortium
Oct 9, 2014·Annual Review of Pharmacology and Toxicology·Henry M DunnenbergerMary V Relling
Sep 26, 2015·Science·Iñigo Martincorena, Peter J Campbell
Oct 16, 2015·Nature·Mary V Relling, William E Evans
Jan 17, 2017·Clinical Pharmacology and Therapeutics·J A LuzumUNKNOWN Pharmacogenomics Research Network Translational Pharmacogenetics Program
Dec 2, 2017·Clinical Pharmacology and Therapeutics·Teri E Klein, Marylyn D Ritchie

❮ Previous
Next ❯

Citations

Sep 10, 2019·Nucleic Acids Research·Jiayi YinFeng Zhu
Sep 24, 2019·Clinical Pharmacology and Therapeutics·Charity NofzigerAndrea Gaedigk
Nov 28, 2019·Briefings in Bioinformatics·Jussi Paananen, Vittorio Fortino
May 5, 2020·PloS One·Joo Young Hong, Ju Han Kim
Jul 6, 2020·Human Molecular Genetics·Jessica A CastrillonFeixiong Cheng
Jul 30, 2020·Molecular Informatics·Bryan DafnietOlivier Taboureau
Sep 5, 2019·Scientific Data·Anthony MammolitiBenjamin Haibe-Kains
Sep 30, 2020·Nucleic Acids Research·María Peña-ChiletJoaquín Dopazo
Oct 1, 2020·Vox Sanguinis·Willy Albert FlegelWilliam Douglas Figg
May 10, 2018·Human Molecular Genetics·Lucila Ohno-MachadoMichael A Hogarth
May 28, 2019·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Thomas Litman
Aug 10, 2019·Journal of Personalized Medicine·Catriona Hippman, Corey Nislow
Jun 30, 2019·Pharmacogenomics·Susanne B Haga, Jivan Moaddeb
Aug 28, 2019·Pharmacogenomics·Laura B RamseyJeffrey R Strawn
Oct 12, 2019·Nucleic Acids Research·David S WishartMiguel Ramirez-Gaona
May 12, 2020·Frontiers in Pharmacology·José Jaime Martínez-MagañaHumberto Nicolini
Jul 16, 2020·Nature Communications·Sepideh SadeghJan Baumbach
Aug 23, 2020·Genes·Roberto SpreaficoAmalio Telenti
Nov 27, 2018·Nucleic Acids Research·Rose OughtredMike Tyers
Apr 23, 2020·International Journal of Molecular Medicine·Jianghuai JiDongguo Li
Feb 6, 2020·Cold Spring Harbor Molecular Case Studies·Melissa A WilkElizabeth A Worthey
Apr 17, 2020·International Journal of Molecular Sciences·Gladys G OliveraMaría José Herrero
Feb 27, 2020·Nutrients·Matteo FlorisMargherita Maioli
Oct 13, 2020·Nucleic Acids Research·Jiayi YinFeng Zhu
Oct 24, 2020·Nucleic Acids Research·Qi PanChun-Quan Li
Nov 3, 2020·Nucleic Acids Research·Kevin L HowePaul Flicek
Dec 15, 2020·Mayo Clinic Proceedings·Wayne T NicholsonAnn M Moyer
Jan 20, 2021·British Journal of Clinical Pharmacology·Essra YoussefTracey Thornley
Jan 14, 2020·Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy·A ToliosT Mohr
Jan 7, 2020·Seminars in Cancer Biology·Naiem T IssaSivanesan Dakshanamurthy
Dec 28, 2019·Computational Biology and Chemistry·Aniruddha AdhikariSamir Kumar Pal
Jan 21, 2021·Pharmacogenomics and Personalized Medicine·Hang TongLy Le

❮ Previous
Next ❯

Software Mentioned

Pharmacogenomics Clinical Annotation Tool ( PharmCAT
CPIC
PGx
PharmCAT
PharmGKB

Related Concepts

Related Feeds

BioHub - Researcher Network

The Chan-Zuckerberg Biohub aims to support the fundamental research and develop the technologies that will enable physicians to cure, prevent, or manage all diseases in our childrens' lifetimes. The CZ Biohub brings together researchers from UC Berkeley, Stanford, and UCSF. Find the latest research from the CZ Biohub researcher network here.

Related Papers

Methods in Molecular Biology
Caroline F ThornRuss B Altman
Clinical Pharmacology and Therapeutics
M Whirl-CarrilloTeri E Klein
American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Kelly E CaudleTeri E Klein
© 2022 Meta ULC. All rights reserved