Pharyngeal cavity and the gills are the target organ for the repellent action of pardaxin in shark

Experientia
N Primor

Abstract

Pardaxin, an active principle of the repellent secretion of the Red Sea flatfish, Pardachirus marmoratus, elicited severe struggling, mouth paralysis, and transient increase in urea leakage from the gills only when administered to the medium bathing the shark's pharyngeal cavity and gills. An apparatus was constructed which prevents a mixing of the outflow from shark's gills with water bathing its surface skin. It is concluded that in sharks the gills and/or the pharyngeal cavity are the target organ for the repellent action of pardaxin.

References

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Citations

Sep 1, 1994·Toxicon : Official Journal of the International Society on Toxinology·D Mebs
Aug 5, 2004·The Journal of Biological Chemistry·Fernando PorcelliGianluigi Veglia
Mar 10, 2009·Toxicon : Official Journal of the International Society on Toxinology·D Mebs
Jun 13, 2014·Integrative Zoology·Nathan S Hart, Shaun P Collin
Feb 18, 2010·Biophysical Journal·Brian S VadDaniel E Otzen
Jul 19, 2002·Biophysical Journal·Kevin J HallockAyyalusamy Ramamoorthy

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