Pharyngeal cavity and the gills are the target organ for the repellent action of pardaxin in shark

N Primor


Pardaxin, an active principle of the repellent secretion of the Red Sea flatfish, Pardachirus marmoratus, elicited severe struggling, mouth paralysis, and transient increase in urea leakage from the gills only when administered to the medium bathing the shark's pharyngeal cavity and gills. An apparatus was constructed which prevents a mixing of the outflow from shark's gills with water bathing its surface skin. It is concluded that in sharks the gills and/or the pharyngeal cavity are the target organ for the repellent action of pardaxin.


Sep 23, 1975·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·B L Roberts, P Witkovsky
Jan 1, 1984·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·N PrimorJ N Forrest
Jan 1, 1983·Journal of Cancer Research and Clinical Oncology·J IzquierdoW Hanna
Nov 1, 1984·Archives of Toxicology·E Zlotkin, S H Gruber
Oct 1, 1984·Pflügers Archiv : European journal of physiology·K L Shepard
Jan 1, 1984·The American Journal of Anatomy·R de Vries, S de Jager
Dec 16, 1980·Biochimica Et Biophysica Acta·N Primor, A T Tu


Sep 1, 1994·Toxicon : Official Journal of the International Society on Toxinology·D Mebs
Aug 5, 2004·The Journal of Biological Chemistry·Fernando PorcelliGianluigi Veglia
Mar 10, 2009·Toxicon : Official Journal of the International Society on Toxinology·D Mebs
Jun 13, 2014·Integrative Zoology·Nathan S Hart, Shaun P Collin
Feb 18, 2010·Biophysical Journal·Brian S VadDaniel E Otzen
Jul 19, 2002·Biophysical Journal·Kevin J HallockAyyalusamy Ramamoorthy

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