PMID: 15224834Jul 1, 2004Paper

Pharyngeal wall collapse and multiple synchronous airway lesions

The Annals of Otology, Rhinology, and Laryngology
Anat ShatzEitan Kerem

Abstract

Pharyngeal wall inspiratory collapse (PWIC) is a dynamic obstruction of the air column proximal to the glottis during inspiration. Our objectives were to assess PWIC's incidence and its contribution to the symptoms of upper airway obstruction (UAO), and to propose indications for intervention. In a retrospective review of consecutive endoscopic evaluations and clinical data of 108 infants with UAO, PWIC was diagnosed in 50 infants (46%). The most common presenting symptom was apnea (52%). The PWIC was accompanied by 2 to 7 synchronous airway abnormalities, most frequently laryngomalacia (78%). Generalized hypotonia was the most common associated systemic finding (80%). Severe PWIC cases required bi-level positive airway pressure (BiPAP). The severity of PWIC, measured by a newly developed classification, was positively correlated to apnea (p < .05) and the need for BiPAP (p < .054). Spontaneous recovery occurred within 36 months. The incidence of PWIC among infants with UAO is high, and its role in UAO deserves greater recognition. Better diagnosis of PWIC will improve the treatment of UAO.

References

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Citations

Dec 29, 2015·Paediatric Respiratory Reviews·Andreas Pfleger, Ernst Eber
Jan 13, 2009·Pediatric Clinics of North America·Ian Brent Masters
Feb 23, 2008·International Journal of Pediatric Otorhinolaryngology·Eilon KrashinYakov Sivan
Jun 15, 2007·The Annals of Otology, Rhinology, and Laryngology·Richard ZoumalanLauren D Holinger
Feb 28, 2018·Frontiers in Pediatrics·Prabhjot K BediJoanna E MacLean
Nov 17, 2020·Frontiers in Pediatrics·Mohammad Ashkan Moslehi
Apr 1, 2021·Pediatrics International : Official Journal of the Japan Pediatric Society·Masanori WasaRei Kitamura

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