Phase behavior and coassembly of DNA and lysozyme in dilute aqueous mixtures: a model investigation of DNA-protein interactions

Langmuir : the ACS Journal of Surfaces and Colloids
Dan LundbergBjörn Lindman

Abstract

Results from an experimental investigation of the phase behavior of an aqueous system of DNA from salmon testes and the protein lysozyme are presented. At very low concentrations of either or both of the macromolecular components, wormlike assemblies with a width of the order of 10 nm are formed. There are strong indications that direct interactions between the protein units are instrumental both in driving the phase separation and in controlling the morphology of the formed assemblies.

References

Sep 1, 1994·Biopolymers·N I KorolevI A Kuznetsov
Apr 13, 2005·Biochemistry·Mikael Lund, Bo Jönsson
May 5, 2005·Annual Review of Biophysics and Biomolecular Structure·Nicholas V Hud, Igor D Vilfan
Apr 29, 2008·Journal of Colloid and Interface Science·Sylwia GawedaM Graça Miguel

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Citations

Jan 26, 2011·Physical Chemistry Chemical Physics : PCCP·Fu-Gen WuZhi-Wu Yu
Nov 23, 2011·Radiation Research·Melissa LeeJamie R Milligan
Jul 17, 2012·Journal of Colloid and Interface Science·Salomé dos SantosBjörn Lindman
May 26, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Agnes MichanekEmma Sparr

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