PMID: 8466937Apr 7, 1993Paper

Phase behavior of mixtures of DPPC and POPG

Biochimica Et Biophysica Acta
T WiedmannV Wong

Abstract

The phase relation of dipalmitoylphosphatidylcholine (DPPC) and 1-palmitoyl-2-oleoyl-phosphatidylglycerol (POPG) has been determined by measurement of the endothermic transitions of mixtures of DPPC and POPG in 100 mM NaCl, 50 mM PIPES (pH 7.0). With the use of differential scanning calorimetry, the gel-liquid crystalline phase transitions of pure POPG and DPPC were estimated to be 274 K and 315.8 K, respectively. With mixtures, there was considerable broadening of the endotherms, but there was no evidence of immiscibility. At high and low mole fractions of DPPC, the observed transition regions are not different from that calculated assuming ideal behavior. However in the central region of the phase diagram, there were deviations from both the ideal liquidus and solidus curves. The chemical shift anisotropy of the 13C-labelled carbonyl carbon of pure DPPC was determined as a function of temperature. At 298 K, a broad peak characteristic of axially symmetric motional averaging of the shielding tensor was observed. At a temperature of 300 K, a narrow peak at 173 ppm was superimposed upon the broad peak. The magnitude of the narrow resonance increased with temperature over the range of 300 to 315 K with the spectrum obtained at th...Continue Reading

References

Nov 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·S Mabrey, J M Sturtevant
Jul 1, 1989·The American Review of Respiratory Disease·Y SuzukiK Kogishi

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Citations

Feb 19, 2009·European Biophysics Journal : EBJ·Bretta Russell-SchulzMichael R Morrow
Jun 6, 2002·Chemistry and Physics of Lipids·Rumiana Koynova, Martin Caffrey
Apr 24, 2012·Colloids and Surfaces. B, Biointerfaces·Priyank KulshresthaR Banerjee
Mar 15, 2011·Colloids and Surfaces. B, Biointerfaces·Apurva R Shah, R Banerjee
Apr 1, 2008·Biochimie·Wei ZhaoMikko Karttunen
Sep 25, 2007·Biophysical Journal·Mandeep Singh BakshiNils O Petersen
Nov 14, 2006·Journal of Molecular Biology·Raquel F EpandRichard M Epand
Dec 10, 2015·Journal of Diabetes Research·Zhenyu QianGuanghong Wei
Jun 26, 2013·Biophysical Journal·Matthew C BlosserSarah L Keller
Nov 21, 2012·The Journal of Physical Chemistry. B·Rodrigo M CordeiroMaurício S Baptista
Jun 13, 2018·Scientific Reports·Rosario OlivaLuigi Petraccone
Jun 20, 2020·Journal of Peptide Science : an Official Publication of the European Peptide Society·Rosario OlivaPompea Del Vecchio
Jul 10, 2021·The Journal of Chemical Physics·Shubhadip DasFlorian Müller-Plathe
Oct 18, 2017·ACS Omega·Jaime SameloMaria João Moreno
Mar 2, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Moutusi Manna, Chaitali Mukhopadhyay
Nov 12, 2020·The Journal of Physical Chemistry. B·Hossein EslamiFlorian Müller-Plathe
May 29, 2020·Biochimica Et Biophysica Acta. Biomembranes·Kenta OkunoHideto Matsuyama
Oct 30, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Sara AnselmoValeria Vetri

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