Phase behavior of Phytantriol/water bicontinuous cubic Pn3m cubosomes stabilized by Laponite disc-like particles

Journal of Colloid and Interface Science
François MullerOtto Glatter

Abstract

The present article reports on the specific effects of temperature on Phytantriol-based cubosomes stabilized by inorganic stabilizers as opposed to organic stabilizers. The ability of Laponite to stabilize Phytantriol-based parent bulk phase is first demonstrated. The sub-micron-sized Laponite-stabilized particles were found to be both physically and chemically stable over time. The temperature-induced behavior, both in heating and cooling directions, of these lipid-based cubosomes has been investigated and compared with their polymer-stabilized counterparts (Pluronic F127). This allows us to extract the particular influence of each stabilizer. Whereas an increased hydration of the cubic structure was evidenced at high pH values, this effect was eliminated to compare the specific influence of both stabilizers on these Phytantriol-based cubosomes. Evidence of differences in the relaxation rates of the internal structures with temperature was found for the two stabilizers, in particular in the cooling direction whilst in the heating direction the two stabilizers could be considered as undisruptive. The origin of this difference is discussed.

References

Jan 12, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Anan YaghmurOtto Glatter
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Jul 1, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Liliana de CampoOtto Glatter
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Citations

Feb 24, 2016·International Journal of Pharmaceutics·Nada MatouguiPatrick Saulnier
Jun 10, 2014·Journal of Controlled Release : Official Journal of the Controlled Release Society·Alexandru Zabara, Raffaele Mezzenga
Sep 27, 2012·Journal of Colloid and Interface Science·Sandra EngelskirchenOtto Glatter
Dec 30, 2014·Colloids and Surfaces. B, Biointerfaces·Amelia M Avachat, Shreekrishna S Parpani
Jul 30, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Josephine Y T ChongCalum J Drummond
Dec 25, 2010·Physical Chemistry Chemical Physics : PCCP·Chandrashekhar V KulkarniSilvia Ahualli
Dec 14, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Martin Dulle, Otto Glatter
Jul 27, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Christa NilssonAnan Yaghmur
Sep 14, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Wye-Khay FongBen J Boyd
Sep 14, 2016·Journal of Colloid and Interface Science·Wye-Khay FongBen J Boyd
Sep 9, 2016·Molecular Pharmaceutics·Letícia RodriguesMadlen Hubert
Nov 3, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Chandrashekhar V KulkarniMichael Rappolt
Mar 23, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Sonal Deshpande, Neetu Singh
May 23, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Yong TianLingyi Sun
Jan 15, 2021·Colloids and Surfaces. B, Biointerfaces·Marco FornasierSergio Murgia
Mar 4, 2021·Journal of Nanoscience and Nanotechnology·Sergio MurgiaClaudia Caltagirone
Jun 15, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Franz PiroltGregor Trimmel

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