Phase-dependent chronotropic response of the heart during running in humans

European Journal of Applied Physiology
Kunihiko NomuraYasuyoshi Yanagida

Abstract

Heartbeat modulation by muscle contraction during rhythmic exercise involving a small muscle mass is phase-dependent, reflecting the timing of the muscle contraction within the cardiac cycle, but it remains unclear whether such modulation occurs during whole body exercise. To determine whether phase-dependent chronotropic changes in the heart would occur during running, we investigated the relationship between R-R interval (RRI) and the timing of vastus lateralis muscle contractions within the cardiac cycle. Seven healthy subjects were examined during high intensity running where the target heart rate was 160 beats . min(-1). The running pitch was made to wax and wane periodically in the neighborhood of the target heart rate to scan the effect of footfall timing within the cardiac cycle on heart period. We found that when muscle contraction occurred early in the cardiac cycle, RRI was reduced from the mean RRI (P<0.05). Conversely, when muscle contraction occurred in the latter half of the cardiac cycle, RRI tended to increase (P>0.05). Thus, the curve reflecting this phase-dependent relationship between heart period and timing of muscle contraction showed a positive slope within the first one-quarter to three-quarters of the c...Continue Reading

References

Nov 1, 1977·The Journal of Physiology·R R Bechbache, J Duffin
Apr 1, 1992·Journal of Applied Physiology·R L KirbyD A MacLeod
May 1, 1992·Journal of Applied Physiology·R B BanzettG P Topulos
Sep 1, 1991·Journal of Applied Physiology·Y YamamotoJ C Peterson
Oct 1, 1991·Immunology and Cell Biology·K J Turner
Dec 1, 1991·Perceptual and Motor Skills·R L KirbyD A MacLeod
Apr 1, 1991·Circulation Research·J M AnumonwoJ Jalife
Feb 1, 1991·Medicine and Science in Sports and Exercise·D A MahlerT A Stukel
Dec 1, 1990·Perceptual and Motor Skills·R L KirbyD A MacLeod
Jan 1, 1989·Journal of Applied Physiology·R L KirbyA E Marble
Jan 1, 1986·European Journal of Applied Physiology and Occupational Physiology·D J PatersonJ D Henstridge
Jan 21, 1983·Science·D M Bramble, D R Carrier
Nov 1, 1993·The Journal of Physiology·P Bernasconi, J Kohl
Aug 1, 1996·Journal of Applied Physiology·B CasadeiP Sleight
Feb 14, 1998·The Journal of General Physiology·E E VerheijckA C van Ginneken
Nov 24, 1998·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·M G RosenblumH H Abel
Mar 10, 1999·Progress in Biophysics and Molecular Biology·P KohlD Noble
Jul 23, 1999·Medicine and Science in Sports and Exercise·M H Laughlin, W G Schrage
Sep 14, 1999·European Journal of Applied Physiology and Occupational Physiology·C Capelli
Jun 22, 2001·European Journal of Applied Physiology·K NomuraY Yanagida
May 9, 2003·European Journal of Applied Physiology·Kunihiko NomuraYasuyoshi Yanagida
Jan 31, 2004·American Journal of Physiology. Heart and Circulatory Physiology·P GrossmanM Spoerle

❮ Previous
Next ❯

Citations

Dec 23, 2011·Journal of Strength and Conditioning Research·Rocco Di MicheleFranco Merni
Nov 6, 2012·Scandinavian Journal of Medicine & Science in Sports·T S LyngeraaF C Pott
Jan 12, 2017·European Journal of Applied Physiology·Lucenildo Silva CerqueiraJurandir Nadal
Dec 15, 2017·Medicine and Science in Sports and Exercise·Keren ConstantiniRobert F Chapman
Mar 3, 2009·American Journal of Physiology. Heart and Circulatory Physiology·Grégory BlainStéphane Bermon
Jul 30, 2021·Neuroscience Letters·Daniela De BartoloMarco Iosa

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.