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Phase i trials in melanoma: A framework to translate preclinical findings to the clinic

bioRxiv

Mar 3, 2015

Eun-Jung KimAlexander R. A. Anderson

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Abstract

We present a, mathematical model driven, framework to implement virtual or imaginary clinical trials (phase i trials) that can be used to bridge the gap between preclinical studies and the clinic. The trial implementation process includes the development of an experimentally validated m...read more

Mentioned in this Paper

Melanoma Pathway
Treatment Protocols
Evaluation
Validation
Clinical Trial [Publication Type]
Clinical Trials
Population Group
Melanoma
Administration of Antineoplastic Agent
Melanoma vaccine
16
2
15
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  • Phase i trials in melanoma: A framework to translate preclinical findings to the clinic

    bioRxiv

    Mar 3, 2015

    Eun-Jung KimAlexander R. A. Anderson

    PMID: 990015925

    DOI: 10.1101/015925

    Abstract

    We present a, mathematical model driven, framework to implement virtual or imaginary clinical trials (phase i trials) that can be used to bridge the gap between preclinical studies and the clinic. The trial implementation process includes the development of an experimentally validated m...read more

    Mentioned in this Paper

    Melanoma Pathway
    Treatment Protocols
    Evaluation
    Validation
    Clinical Trial [Publication Type]
    16
    2
    15

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