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Phase II dose-response study of abatacept in Japanese patients with active rheumatoid arthritis with an inadequate response to methotrexate

Modern Rheumatology

Jun 12, 2012

Tsutomu TakeuchiJapan Abatacept Study Group

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Abstract

The objective of this study was to assess the response to abatacept at doses of 2 mg/kg and 10 mg/kg compared to placebo in patients with active rheumatoid arthritis (RA) with an inadequate clinical response to methotrexate (MTX). In this multicenter, placebo-controlled, double-blind, p...read more

Mentioned in this Paper

Antirheumatic Drugs, Disease-Modifying
Dose-response Relationship
Abatacept
Adverse Event
Rheumatoid Arthritis
BMS 188667
Radioimmunoconjugates
Response to Methotrexate
Rheumatology Specialty
Methotrexate, (DL)-Isomer
Paper Details
References
  • References28
  • Citations5
123

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Phase II dose-response study of abatacept in Japanese patients with active rheumatoid arthritis with an inadequate response to methotrexate

Modern Rheumatology

Jun 12, 2012

Tsutomu TakeuchiJapan Abatacept Study Group

PMID: 22684431

DOI: 10.1007/s10165-012-0668-z

Abstract

The objective of this study was to assess the response to abatacept at doses of 2 mg/kg and 10 mg/kg compared to placebo in patients with active rheumatoid arthritis (RA) with an inadequate clinical response to methotrexate (MTX). In this multicenter, placebo-controlled, double-blind, p...read more

Mentioned in this Paper

Antirheumatic Drugs, Disease-Modifying
Dose-response Relationship
Abatacept
Adverse Event
Rheumatoid Arthritis
BMS 188667
Radioimmunoconjugates
Response to Methotrexate
Rheumatology Specialty
Methotrexate, (DL)-Isomer

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Related Papers

Paper Details
References
  • References28
  • Citations5
123

Download from

Publisher
PubMed
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