Abstract
Cavernous sinus hemangioma is a rare vascular tumor. The direct microsurgical approach usually results in massive hemorrhage. Although radiosurgery plays an important role in managing cavernous sinus hemangiomas as a treatment alternative to microsurgery, the potential for increased toxicity with single-session treatment of large tumors is a concern. The purpose of this study was to assess the efficacy of hypofractionated stereotactic radiotherapy in patients with large cavernous sinus hemangiomas. Fourteen patients with large (volume >20 cm(3)) cavernous sinus hemangiomas were enrolled in a prospective Phase II study between December 2007 and December 2010. The hypofractionated stereotactic radiotherapy dose was 21 Gy delivered in 3 fractions. After a mean follow-up of 15 months (range, 6-36 months), the magnetic resonance images showed a mean of 77% tumor volume reduction (range, 44-99%). Among the 6 patients with cranial nerve impairments before hypofractionated stereotactic radiotherapy, 1 achieved symptomatic complete resolution and 5 had improvement. No radiotherapy-related complications were observed during follow-up. Our current experience, though preliminary, substantiates the role of hypofractionated stereotactic radi...Continue Reading
References
Jan 1, 1992·Neurosurgery·M E Linskey, L N Sekhar
Sep 30, 1993·International Journal of Radiation Oncology, Biology, Physics·R B TishlerJ C Flickinger
Jan 1, 1996·Neurosurgical Review·A B Jamjoom
Jun 8, 1999·Neurologia Medico-chirurgica·Y IwaiT Yasui
Sep 12, 2000·Neurosurgery·T P ThompsonJ C Flickinger
Apr 2, 2004·Acta neurochirurgica·S PekerM N Pamir
May 26, 2004·Neurosurgery·John S KuoMichael L J Apuzzo
Mar 8, 2006·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Anca L Grosu, Carsten Nieder
Jun 4, 2008·Minimally Invasive Neurosurgery : MIN·P IvanovK Takakura
Feb 26, 2009·Skull Base : Official Journal of North American Skull Base Society ... [et Al.]·Justin F FraserTheodore H Schwartz
Jul 21, 2009·Journal of Neurosurgery·Masaaki YamamotoToru Serizawa
Oct 17, 2009·Neurosurgery·Aftab A KhanL Dade Lunsford
Mar 5, 2010·International Journal of Radiation Oncology, Biology, Physics·Charles MayoJohn Kirkpatrick
Jul 22, 2010·Neurosurgery·Chiang-Wei ChouDavid Hung-Chi Pan
Citations
Apr 12, 2015·Acta neurochirurgica·Xuqun TangLi Pan
Oct 19, 2017·Radiation Oncology Journal·Sunmin ParkEun Kyung Choi
Mar 17, 2017·Journal of Neurosurgery·Xin WangEnmin Wang
Mar 4, 2014·Journal of Neuro-oncology·Sang Woo SongHee-Won Jung
Sep 19, 2019·Technology in Cancer Research & Treatment·Lichao HuangLong Sheng Pan
Jun 2, 2020·Frontiers in Neurology·Zengfeng XinTing Zhang
Aug 14, 2019·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Dorota Księżniak-BaranMaja Jędrzejewska
Sep 11, 2019·World Neurosurgery·Yun GuanXin Wang
Nov 15, 2021·World Neurosurgery·Xiyao WuRisheng Liang