PMID: 8600093Mar 15, 1996Paper

Phase III study of interstitial thermoradiotherapy compared with interstitial radiotherapy alone in the treatment of recurrent or persistent human tumors. A prospectively controlled randomized study by the Radiation Therapy Group

International Journal of Radiation Oncology, Biology, Physics
B EmamiEduardo Moros

Abstract

The objectives of this randomized trial were to determine if interstitial thermoradiotherapy (ITRT) improves tumor regression/control in accessible lesions in comparison with interstitial radiotherapy (IRT) alone and to assess the skin and soft tissue complications with either modality. From January 1986 to June 1992, 184 patients with persistent or recurrent tumors after previous radiotherapy and/or surgery, which were amenable to interstitial radiotherapy, were accessioned to a protocol developed by the Radiation Therapy Oncology Group (RTOG). One hundred seventy-three cases were analyzed (87 patients in the IRT group and 86 in the ITRT arm). The two arms were well balanced regarding stratification criteria. Most tumors were in the head and neck (40% in the IRT group and 46% in the ITRT group), and pelvis (42% and 43%, respectively). Eighty-four percent of patients in both arms had prior radiation therapy (> or = 40 Gy); 50% and 40%, respectively, had prior surgery, and 34% in each arm had prior chemotherapy. The dose of radiation therapy administered was dependent on the previous radiation dose and did not exceed a total cumulative dose of 100 Gy. Hyperthermia was delivered in one or two sessions, either before or before and...Continue Reading

References

Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·P K SneedD K Ahn
May 1, 1991·International Journal of Radiation Oncology, Biology, Physics·B EmamiT Samulski
Feb 1, 1990·International Journal of Radiation Oncology, Biology, Physics·D S ShimmT C Cetas
Apr 1, 1986·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·R ValdagniC Valdagni
May 1, 1988·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·K LamZ Petrovich
Mar 1, 1987·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·B EmamiD Vongerichten
Jan 1, 1985·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·J M CossetJ A Dewar
Jul 1, 1983·Radiology·C T CoughlinT Z Wong
Aug 1, 1983·International Journal of Radiation Oncology, Biology, Physics·G ArcangeliF Mauro
Dec 1, 1984·American Journal of Clinical Oncology·B EmamiD Von Gerichten
Jun 1, 1981·International Journal of Radiation Oncology, Biology, Physics·C D JosephF W George
Feb 1, 1980·International Journal of Radiation Oncology, Biology, Physics·G ArcangeliA Tabocchini

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Citations

Jun 7, 2005·International Journal of Radiation Oncology, Biology, Physics·Jacoba van der ZeePeter Wust
Apr 24, 2001·International Journal of Radiation Oncology, Biology, Physics·U M SchleicherJ Ammon
Aug 3, 2001·International Journal of Radiation Oncology, Biology, Physics·S NagUNKNOWN American Brachytherapy Society
Sep 25, 2001·International Journal of Radiation Oncology, Biology, Physics·A PuthawalaV Nixon
May 15, 2002·International Journal of Radiation Oncology, Biology, Physics·Marco van VulpenJan J Battermann
Sep 6, 2003·International Journal of Radiation Oncology, Biology, Physics·Mark W Dewhirst, Penny K Sneed
Feb 11, 1998·International Journal of Radiation Oncology, Biology, Physics·P K SneedP H Gutin
Jul 6, 2002·Critical Reviews in Oncology/hematology·Bert HildebrandtHanno Riess
Aug 16, 2002·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J van der Zee
Dec 19, 2009·Current Opinion in Obstetrics & Gynecology·Martine Franckena, Jacoba van der Zee
Jul 31, 2002·The Lancet Oncology·P WustP M Schlag
Dec 17, 2014·Seminars in Oncology·Mark Hurwitz, Paul Stauffer
Jan 14, 2016·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Gerard C van Rhoon
May 12, 2007·Clinical Oncology : a Journal of the Royal College of Radiologists·M R Horsman, J Overgaard
Jul 21, 2005·International Journal of Radiation Oncology, Biology, Physics·Jaroslaw T HepelPaul Frankel
Nov 29, 2014·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Samuel PichardoKullervo Hynnyen
Jun 14, 2012·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Richard A M CantersGerard C van Rhoon
Aug 21, 2013·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Ryan M DavisMark W Dewhirst
Jan 13, 2015·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Vratislav StrnadRainer Fietkau
Jan 1, 2011·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Adam ChichełMarek Kanikowski
Aug 19, 2016·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Carsten NiederAnca L Grosu
Jan 5, 1999·IEEE Transactions on Medical Imaging·J De BreeJ J Battermann
Nov 4, 2016·Medical Physics·Gregory WarrellE Ishmael Parsai
Feb 7, 2007·Medical Physics·Eduardo G MorosColin G Orton
Jan 26, 2017·Journal of Controlled Release : Official Journal of the Controlled Release Society·Yannan DouChristine Allen
May 14, 1999·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·J CrezeeJ J Lagendijk
Nov 10, 2001·Annual Review of Biomedical Engineering·R B Roemer
Jul 1, 1997·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·J F van der KoijkJ J Battermann
Aug 5, 1998·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·I S Khalil-BustanyC Kirjner-Neto
Apr 9, 2008·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Hunter R Moyer, Keith A Delman
Nov 12, 2019·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Chenchen BingRajiv Chopra
Nov 12, 2019·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Niloy Ranjan Datta, Stephan Bodis
Feb 20, 2008·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·J van der ZeeT Sugahara
Jul 10, 2009·The Cochrane Database of Systematic Reviews·Danielle F M De Haas-KockJacoba van der Zee
Jul 6, 2010·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Thomas P RyanBrianne Hamilton
Dec 22, 1999·Acta Oncologica·O DahlO Mella

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