Phase III trial of oral magnetic particles in MRI of abdomen and pelvis

Clinical Radiology
D MacVicarJ E Husband

Abstract

A prospective Phase III trial was performed to evaluate the efficacy in clinical practice of a new gastro-intestinal contrast agent, Oral Magnetic Particles (OMP), for use in abdominal and pelvic magnetic resonance imaging (MRI). This was an open study comprising 35 patients each given 800 ml of OMP at a concentration of 0.5 g/l. Distribution of the agent was most reliable in the small bowel. General contrast effect was satisfactory, and image quality and diagnostic confidence were enhanced. Administration of OMP increased diagnostic information in the magnetic resonance (MR) image in 50% of patients. No clinically significant adverse effects were observed. The results confirm in a clinical setting a potential role for this new contrast agent.

References

Jun 1, 1992·Clinical Radiology·J E HusbandG Thomas
Mar 1, 1991·Radiology·P A RinckA Børseth
Apr 1, 1988·AJR. American Journal of Roentgenology·M LaniadoR Felix

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Citations

Mar 13, 2001·The Journal of Maternal-fetal Medicine·D M TwicklerB Rogers
May 1, 1997·Journal of Magnetic Resonance Imaging : JMRI·O ErnstC L'Hermine
Oct 6, 1997·Journal of Magnetic Resonance Imaging : JMRI·D L RubinS W Young
Dec 24, 1997·Journal of Magnetic Resonance Imaging : JMRI·J ScheidlerM F Reiser
Jul 1, 1997·European Journal of Radiology·P TervahartialaC G Standertskjöld-Nordenstam
Jul 14, 2001·Current Opinion in Obstetrics & Gynecology·P PahlavanC Nezhat
Nov 15, 2001·Current Opinion in Obstetrics & Gynecology·H A Mousa, S Walkinshaw
May 10, 2001·Clinical Obstetrics and Gynecology·S C Goodwin, G C Wong
Apr 11, 2003·Clinical Obstetrics and Gynecology·Bruce McLucas
Aug 14, 1998·Obstetrical & Gynecological Survey·L HudonD R Broome
Dec 22, 1999·Obstetrical & Gynecological Survey·O Abulafia, D M Sherer
Jan 27, 2005·Obstetrical & Gynecological Survey·Natalie Paloma Cooper, Stanley Okolo
Jul 20, 2007·Obstetrical & Gynecological Survey·Stergios K DoumouchtsisSabaratnam Arulkumaran
Feb 10, 2010·Clinical Obstetrics and Gynecology·Justin S Lee, Suzanne M Shepherd
Nov 27, 2009·Obstetrical & Gynecological Survey·Ella OphirJacob Bornstein
May 8, 2007·Journal of Perinatal Medicine·Istvan SzillerZoltán Papp
Apr 1, 1996·Clinical Radiology·W SchimaS Saini
Sep 1, 1995·Journal of Magnetic Resonance Imaging : JMRI·S W YoungR A Miller

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