Phase-locked responses to the vowel envelope vary in scalp-recorded amplitude due to across-frequency response interactions

The European Journal of Neuroscience
Vijayalakshmi EaswarDavid W Purcell

Abstract

Neural encoding of the envelope of sounds like vowels is essential to access temporal information useful for speech recognition. Subcortical responses to envelope periodicity of vowels can be assessed using scalp-recorded envelope following responses (EFRs); however, the amplitude of EFRs vary by vowel spectra and the causal relationship is not well understood. One cause for spectral dependency could be interactions between responses with different phases, initiated by multiple stimulus frequencies. Phase differences can arise from earlier initiation of processing high frequencies relative to low frequencies in the cochlea. This study investigated the presence of such phase interactions by measuring EFRs to two naturally spoken vowels (/ε/ and /u/), while delaying the envelope phase of the second formant band (F2+) relative to the first formant (F1) band in 45° increments. At 0° F2+ phase delay, EFRs elicited by the vowel /ε/ were lower in amplitude than the EFRs elicited by /u/. Using vector computations, we found that the lower amplitude of /ε/-EFRs was caused by linear superposition of F1- and F2+-contributions with larger F1-F2+ phase differences (166°) compared to /u/ (19°). While the variation in amplitude across F2+ phas...Continue Reading

References

Jun 29, 1992·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·S Rosen
Sep 13, 1974·Brain Research·M M Merzenich, M D Reid
Mar 1, 1984·The Journal of the Acoustical Society of America·B Delgutte, N Y Kiang
May 1, 1995·The Journal of the Acoustical Society of America·J HillenbrandK Wheeler
Mar 1, 1993·The Journal of Comparative Neurology·G A SpirouD K Ryugo
Feb 8, 2000·Computer Methods and Programs in Biomedicine·M S John, T W Picton
Mar 30, 2000·The Journal of the Acoustical Society of America·T DauB Kollmeier
Jun 9, 2000·Annual Review of Neuroscience·C E SchreinerM L Sutter
Mar 16, 2001·The Journal of the Acoustical Society of America·J M HillenbrandT M Nearey
Jun 28, 2001·Physiological Reviews·L Robles, M A Ruggero
May 15, 2002·Audiology & Neuro-otology·Jos J Eggermont, Curtis W Ponton
Oct 26, 2002·The Journal of the Acoustical Society of America·Anthony T HerdmanDavid R Stapells
Jan 23, 2003·Brain Topography·Anthony T HerdmanTerence W Picton
Oct 10, 2003·Ear and Hearing·M S JohnT W Picton
Jan 22, 2005·The Journal of the Acoustical Society of America·David W PurcellTerence W Picton
Apr 23, 2005·Journal of the American Academy of Audiology·Terence W PictonPatricia Van Roon
Jul 15, 2005·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Manuel DonChiemi Tanaka
Apr 14, 2006·Audiology & Neuro-otology·Steven J Aiken, Terence W Picton
Jul 27, 2006·Journal of the American Academy of Audiology·Ekkehard StürzebecherThomas Berger
Jan 15, 2008·The Journal of the Acoustical Society of America·Claus ElberlingEkkehard Stürzebecher
Feb 23, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·I AkhounH Thai-Van
Sep 4, 2008·Hearing Research·Steven J Aiken, Terence W Picton
Oct 4, 2008·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Elsa ErixonHelge Rask-Andersen
Jul 21, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jane HornickelNina Kraus
Jul 24, 2010·The Journal of the Acoustical Society of America·Claus ElberlingManuel Don
Aug 5, 2010·Journal of Cognitive Neuroscience·Judy H SongNina Kraus
Jan 28, 2012·The Journal of the Acoustical Society of America·Magdalena WojtczakAndrew J Oxenham
Jul 6, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Matthew J McGinleyDonata Oertel
Oct 18, 2012·Journal of the American Academy of Audiology·Sinnet G B Kristensen, Claus Elberling
Apr 12, 2013·Ear and Hearing·Jong Min ChoiSteven J Aiken
Jul 19, 2013·The Journal of the Acoustical Society of America·Li ZhuBarbara Shinn-Cunningham
Sep 15, 2015·Hearing Research·Sara K MamoEmily Buss
Dec 11, 2017·Neuroscience Letters·Vijayalakshmi EaswarDavid Purcell

❮ Previous
Next ❯

Citations

Jan 25, 2019·International Journal of Audiology·Frederique J VanheusdenSteven L Bell
Aug 10, 2020·Ear and Hearing·Vijayalakshmi EaswarDavid Purcell
Dec 29, 2020·Ear and Hearing·Saradha AnanthakrishnanDanielle Yurjevich
Nov 3, 2020·Ear and Hearing·Vijayalakshmi EaswarDavid Purcell
Jul 7, 2021·Hearing Research·Vijayalakshmi EaswarRegan Flaherty
Jul 13, 2021·Trends in Hearing·Vijayalakshmi EaswarDavid W Purcell
Jul 15, 2021·Ear and Hearing·Vijayalakshmi EaswarDavid Purcell

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.