Phase of Spontaneous Slow Oscillations during Sleep Influences Memory-Related Processing of Auditory Cues

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Laura J BatterinkKen A Paller

Abstract

Slow oscillations during slow-wave sleep (SWS) may facilitate memory consolidation by regulating interactions between hippocampal and cortical networks. Slow oscillations appear as high-amplitude, synchronized EEG activity, corresponding to upstates of neuronal depolarization and downstates of hyperpolarization. Memory reactivations occur spontaneously during SWS, and can also be induced by presenting learning-related cues associated with a prior learning episode during sleep. This technique, targeted memory reactivation (TMR), selectively enhances memory consolidation. Given that memory reactivation is thought to occur preferentially during the slow-oscillation upstate, we hypothesized that TMR stimulation effects would depend on the phase of the slow oscillation. Participants learned arbitrary spatial locations for objects that were each paired with a characteristic sound (eg, cat-meow). Then, during SWS periods of an afternoon nap, one-half of the sounds were presented at low intensity. When object location memory was subsequently tested, recall accuracy was significantly better for those objects cued during sleep. We report here for the first time that this memory benefit was predicted by slow-wave phase at the time of stim...Continue Reading

Citations

Sep 14, 2016·Current Biology : CB·Ping Chai Koo, Lisa Marshall
May 16, 2018·Annals of the New York Academy of Sciences·Nicola Cellini, Alessandra Capuozzo
Nov 11, 2016·Journal of Neurophysiology·Drew B HeadleyDenis Paré
Oct 25, 2017·Cognitive, Affective & Behavioral Neuroscience·Marie Roxanne SoppAxel Mecklinger
Feb 23, 2019·Journal of Neural Engineering·Prathamesh M KulkarniZhe Chen
Feb 23, 2018·Frontiers in Human Neuroscience·Renee E ShimizuStephen B Simons
Jul 12, 2017·Psychonomic Bulletin & Review·Holly J BowenElizabeth A Kensinger
Jan 1, 2016·Neuroscience of Consciousness·Thomas Andrillon, Sid Kouider
Mar 25, 2017·Frontiers in Human Neuroscience·Nelly A PapalambrosPhyllis C Zee
Dec 5, 2019·Physiology·Lisa MarshallThien Thanh Dang-Vu
Apr 2, 2019·Frontiers in Cellular Neuroscience·Jesse J Langille
Feb 26, 2019·Scientific Reports·Maurice GöldiThomas Schreiner
Oct 20, 2020·Frontiers in Neuroscience·Bryce A Mander
Feb 2, 2020·Sleep Medicine Clinics·Roneil G Malkani, Phyllis C Zee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.