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Phase partition studies of actinomycin-nucleotide complexes

Biochemistry

Oct 5, 1976

P Davanloo, Donald M Crothers

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Abstract

A method is reported for measuring the stoichiometry of complex formation between actinomycin and a series of deoxynucleotides. The amount of bound actinomycin is measured by distribution of the drug between two liquid phases, a buffer phase containing deoxynucleotide and an organic pha...read more

Mentioned in this Paper

Complex (molecular entity)
Ac-De
Mathematics
Oligonucleotides
Structure-Activity Relationship
Actinomycin [EPC]
Oligoribonucleotides
Ribonucleotides
Actinomycin
Ligand Binding Domain
Paper Details
References
  • References20
  • Citations14
12

Phase partition studies of actinomycin-nucleotide complexes

Biochemistry

Oct 5, 1976

P Davanloo, Donald M Crothers

PMID: 61763

DOI: 10.1021/bi00665a015

Abstract

A method is reported for measuring the stoichiometry of complex formation between actinomycin and a series of deoxynucleotides. The amount of bound actinomycin is measured by distribution of the drug between two liquid phases, a buffer phase containing deoxynucleotide and an organic pha...read more

Mentioned in this Paper

Complex (molecular entity)
Ac-De
Mathematics
Oligonucleotides
Structure-Activity Relationship

Related Papers

Paper Details
References
  • References20
  • Citations14
12

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