Phenazines and cancer

Natural Product Reports
A CimminoR Kiss

Abstract

Phenazines are a large group of natural and synthesised nitrogen-containing heterocycles, including more than 100 different compounds of natural origin and over 6000 synthetic compounds. Many of these compounds have been investigated as potential anti-cancer agents. Despite a large number of research publications, no recent attempt to summarise and critically evaluate the experimental findings relating to the anti-cancer activity of this class of compounds has been made. The present review fills this gap in the literature and discusses both natural and synthetic phenazines with a critical focus on in vitro, in vivo and available clinical anti-cancer activities of these compounds.

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Citations

Sep 3, 2013·European Journal of Medicinal Chemistry·Xiaochun GaoTao Xi
Oct 28, 2016·Indian Journal of Microbiology·Kontham Kulangara VarshaKesavan Madhavan Nampoothiri
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Sep 26, 2020·Ecotoxicology and Environmental Safety·Jiang OuBaoshan Xing
Nov 3, 2020·ACS Omega·Haruki KohatsuKouji Kuramochi

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