Phenolic alkaloids as a new class of antioxidants in Portulaca oleracea

Phytotherapy Research : PTR
Zijuan YangYinan Zheng

Abstract

Antioxidant activities of three phenolic alkaloids, i.e., oleracein A (OA), oleracein B (OB) and oleracein E (OE), isolated from Portulaca oleracea were determined, based on scavenging activity against 1,1-diphenyl- 2-picryl-hydrazyl (DPPH) radical and inhibitory effect on hydrogen peroxide-induced lipid peroxidation in rat brain homogenates. The DPPH radical scavenging activities of these phenolic alkaloids were lower than caffeic acid but higher than ascorbic acid and alpha-tocopherol, being in the following order: OB > OA > OE. OE was most potent in preventing formation of malondialdehyde (MDA) with an EC(50) value of 73.13 microM, close to that of caffeic acid (72.09 microM). It was demonstrated that phenolic alkaloids served as a new class of antioxidant agents in this plant.

References

Aug 1, 1992·Journal of the American College of Nutrition·A P SimopoulosJ A Duke
Oct 6, 2005·Phytochemistry·Lan XiangLijun Du
Sep 4, 2007·Chemico-biological Interactions·Zhang HongxingHuang Hao

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Citations

Dec 3, 2014·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Y ZidanM Bouchenak
Feb 19, 2016·The Journal of Pharmacy and Pharmacology·Yihan MengXixiang Ying
Jun 12, 2012·Phytochemistry·Jian YanJian-Wen Tan
Apr 12, 2016·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Pei-Pei WangLan Xiang
Nov 26, 2015·International Journal of Preventive Medicine·Elahe ZakizadehAhmad Esmaillzadeh
Feb 19, 2015·BioMed Research International·Yan-Xi ZhouHong Zhang
Dec 11, 2013·Journal of Asian Natural Products Research·Jin-Long TianShao-Jiang Song
Mar 1, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Florea DumitrascuDenisa Dumitrescu
Mar 31, 2018·Current Drug Discovery Technologies·Tahereh FarkhondehSoroush Hozeifi
Jun 1, 2019·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Jung Im LeeYoungwan Seo
Sep 27, 2019·Future Medicinal Chemistry·Maria D MatveevaCosimo D Altomare
Apr 30, 2020·Antioxidants·Isabella RomeoTiziana Marino
Dec 13, 2017·Journal of Evidence-based Complementary & Alternative Medicine·Saeed SamarghandianTahereh Farkhondeh
Aug 30, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Nida Nayyar FarshoriMaqsood Ahmed Siddiqui
Apr 30, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Ebtesam Saad Al-SheddiMaqsood Ahmed Siddiqui
Sep 25, 2020·Food Science of Animal Resources·Sang-Keun Jin, Dong-Gyun Yim
Jun 7, 2021·Bioorganic Chemistry·Jia FuJie Kang
Aug 21, 2021·Natural Product Research·Xilong LiuDidier Stien

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