Phenolics: prooxidants or antioxidants?

Nutrition Reviews
E A Decker

Abstract

Both essential and nonessential dietary antioxidants have been suggested to be beneficial for health. However, studies show that many antioxidants can also exhibit prooxidant behavior under certain conditions. The antioxidant/prooxidant activity of phenolics is dependent on such factors as metal-reducing potential, chelating behavior, pH, and solubility characteristics. These factors, in addition to bioavailability and stability in tissues, should be considered when evaluating the potential bioactivity of dietary phenolics.

References

Feb 1, 1992·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·O I AruomaJ Löligers
Oct 1, 1995·Free Radical Biology & Medicine·A SaijaF Castelli

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Citations

May 12, 2001·The British Journal of Nutrition·K KovaryI Felzenszwalb
Apr 16, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Biljana KaurinovicMilena Raseta
Jul 24, 2014·Anais Da Academia Brasileira De Ciências·Rafaela F LunardiCaroline Dani
Nov 8, 2017·Antioxidants·María Losada-EcheberríaEnrique Barrajón-Catalán
Feb 12, 2019·Journal of Toxicology and Environmental Health. Part a·Joubert Aires De SousaJaqueline Nascimento Picada
Jul 19, 2003·Free Radical Research·L TesoriereM A Livrea
Mar 19, 2008·Basic & Clinical Pharmacology & Toxicology·Harvey BabichAlyssa G Schuck
Feb 10, 2012·Interdisciplinary Toxicology·Zuzana Kyselova
Jul 19, 2011·Cell Biology and Toxicology·Surawat JariyawatPawinee Piyachaturawat
Apr 2, 2015·Journal of Food Science and Technology·V Cijo GeorgeR Ashok Kumar
Mar 29, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Tran Hai BangKuniyoshi Shimizu
Nov 16, 2016·Antioxidants·Hans VergauwenChris van Ginneken
Jul 4, 2017·Journal of the Science of Food and Agriculture·Kubra UnalFatih Oz
Aug 24, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bartosz FotschkiMichał Sójka
Nov 21, 2019·Nanomaterials·Danijel D MilinčićMirjana B Pešić
May 13, 1999·Teratogenesis, Carcinogenesis, and Mutagenesis·M C AraújoC S Takahashi
Jul 17, 1999·The American Journal of Physiology·L L McLeod, A I Alayash
May 18, 2010·Journal of the Science of Food and Agriculture·Jing-en LiMing-yong Xie
Dec 27, 2007·Journal of Medicinal Food·Won O SongSung G Lee
Jan 1, 2008·Nutrition Research and Practice·Jie YinMyeong-Hyeon Wang
Mar 23, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bhakta Prasad GaireHocheol Kim
Feb 11, 2015·Chemical Communications : Chem Comm·Adi Haber, Zeev Gross
Oct 6, 2017·International Journal of Molecular Sciences·Israel Pérez-TorresMaría Esther Rubio-Ruiz
Jan 24, 2018·Journal of Food Science and Technology·Mei ChengZhicheng Zhang
Jun 9, 2018·Biotechnology Progress·Natarajan VijayasankaranRobert Kiss
Oct 17, 2018·Diseases of Aquatic Organisms·Sophia Egloff, Constanze Pietsch
Aug 31, 2019·Journal of Toxicology·Robin A ReddemanIlona Pasics Szakonyiné
Jan 4, 2020·Journal of Food Biochemistry·Andréia Limana TambaraCristiane Casagrande Denardin
Mar 12, 2004·Annual Review of Plant Physiology and Plant Molecular Biology·Michael A. Grusak, Dean DellaPenna
Oct 1, 2007·Nutrition Research and Practice·Jie YinMyeong-Hyeon Wang

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