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Phenomenon of hot-cold hemolysis: chelator-induced lysis of sphingomyelinase-treated erythrocytes

Infection and Immunity

Nov 1, 1975

C J SmythT Wadström

PMID: 333

Abstract

Staphylococcus aureus produces a phospholipase C specific for sphingomyelin (beta-hemolysin). Erythrocytes with approximately 50% sphingomyelin in their membranes, e.g., from sheep, have been shown to have up to 60% of this phospholipid hydrolyzed by this enzyme at 37 C in isotonic buff...read more

Mentioned in this Paper

Pathologic Cytolysis
Buffers
Paraparesis
Cations, Divalent
Tissue Membrane
Pentetates
Phosphoric diester hydrolase
Chelator (genus)
Bipyridyl
Dall Sheep
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Phenomenon of hot-cold hemolysis: chelator-induced lysis of sphingomyelinase-treated erythrocytes

Infection and Immunity

Nov 1, 1975

C J SmythT Wadström

PMID: 333

DOI:

Abstract

Staphylococcus aureus produces a phospholipase C specific for sphingomyelin (beta-hemolysin). Erythrocytes with approximately 50% sphingomyelin in their membranes, e.g., from sheep, have been shown to have up to 60% of this phospholipid hydrolyzed by this enzyme at 37 C in isotonic buff...read more

Mentioned in this Paper

Pathologic Cytolysis
Buffers
Paraparesis
Cations, Divalent
Tissue Membrane
Pentetates
Phosphoric diester hydrolase
Chelator (genus)
Bipyridyl
Dall Sheep

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