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Phenomenon of hot-cold hemolysis: chelator-induced lysis of sphingomyelinase-treated erythrocytes

Infection and Immunity

Nov 1, 1975

Cyril J SmythT Wadström

PMID: 333

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Abstract

Staphylococcus aureus produces a phospholipase C specific for sphingomyelin (beta-hemolysin). Erythrocytes with approximately 50% sphingomyelin in their membranes, e.g., from sheep, have been shown to have up to 60% of this phospholipid hydrolyzed by this enzyme at 37 C in isotonic buff...read more

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Chelator (genus)
Cations
Phenanthrolines
Metal Antagonists
Ethylenediaminetetraacetate
Dall Sheep
Phospholipase C
Tissue Membrane
Buffers
Cations, Divalent
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  • Phenomenon of hot-cold hemolysis: chelator-induced lysis of sphingomyelinase-treated erythrocytes

    Infection and Immunity

    Nov 1, 1975

    Cyril J SmythT Wadström

    PMID: 333

    DOI:

    Abstract

    Staphylococcus aureus produces a phospholipase C specific for sphingomyelin (beta-hemolysin). Erythrocytes with approximately 50% sphingomyelin in their membranes, e.g., from sheep, have been shown to have up to 60% of this phospholipid hydrolyzed by this enzyme at 37 C in isotonic buff...read more

    Mentioned in this Paper

    Chelator (genus)
    Cations
    Phenanthrolines
    Metal Antagonists
    Ethylenediaminetetraacetate

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