Abstract
A case of black-grain mycetoma occurring on the lower jaw with an odontogenic origin, which to our knowledge is the first case reported in China, is presented here. The clinical manifestation, histopathological morphology, and microbiological features are described. The new species, Madurella pseudomycetomatis, isolated from the black grains discharged by this patient, was analyzed using sequence data of the multiloci of ribosomal DNA (rDNA) and its ability to ferment carbohydrate as well as morphology. The analyses of the internal transcribed spacer (ITS) region and the D1/D2 hypervariable region of the 28S ribosomal gene sequences support a new species designation. Antifungal susceptibility testing was conducted, indicating that Madurella pseudomycetomatis was highly susceptible to itraconazole, voriconazole, and amphotericin B; moderately susceptible to terbinafine; and resistant to fluconazole and flucytosine.
References
Nov 1, 1989·Journal of Clinical Microbiology·A Espinel-IngroffT M Kerkering
May 1, 1986·The American Journal of Tropical Medicine and Hygiene·S A GumaaM A el Sid
Dec 1, 1982·Infection and Immunity·C CondeL Ortiz-Ortiz
Sep 1, 1980·Infection and Immunity·H Zlotnik, H R Buckley
Sep 17, 1999·Journal of Clinical Microbiology·A O AhmedA van Belkum
Nov 24, 1999·Current Microbiology·M M LopesP Boiron
Jun 2, 2000·Journal of Clinical Microbiology·Y C ChenB T Cookson
Oct 30, 2001·Journal of Clinical Microbiology·Y C ChenB T Cookson
Mar 7, 2002·Journal of Clinical Microbiology·Abdalla AhmedSybren de Hoog
May 29, 2003·FEMS Immunology and Medical Microbiology·Abdalla O AhmedIrma A J M Bakker-Woudenberg
Oct 9, 2003·Journal of Clinical Microbiology·Abdalla AhmedAlex van Belkum
Dec 10, 2003·Journal of Clinical Microbiology·Abdalla O A AhmedAlex van Belkum
Jan 2, 2004·Transactions of the Royal Society of Tropical Medicine and Hygiene·A H Fahal
Apr 14, 2004·Mycoses·G S de HoogA van Belkum
Jun 25, 2004·Antimicrobial Agents and Chemotherapy·Abdalla O A AhmedIrma A J M Bakker-Woudenberg
Sep 1, 2004·The Lancet Infectious Diseases·Abdalla O A AhmedAlex van Belkum
Jan 5, 2005·Mycopathologia·Raquel VilelaAna C L Moura
Mar 29, 2005·Antimicrobial Agents and Chemotherapy·Wendy W J van de SandeAlex van Belkum
Jul 8, 2005·Journal of Clinical Microbiology·Jennifer L RakemanBrad T Cookson
Sep 8, 2005·Journal of Clinical Microbiology·Wendy W J van de SandeAlex van Belkum
Oct 6, 2006·Journal of Clinical Microbiology·Marie Desnos-OllivierEric Dannaoui
Citations
Mar 26, 2013·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Abhijit JoshiK Gopalkrishnan
Jan 26, 2011·Antimicrobial Agents and Chemotherapy·Alex van BelkumWendy W J van de Sande
Apr 6, 2011·Journal of Clinical Microbiology·Arvind A Padhye, Ira F Salkin
Dec 30, 2011·Journal of Clinical Microbiology·G Sybren de HoogWendy W J van de Sande
Oct 1, 2011·Medical Mycology·V Vinod MoothaG Sybren de Hoog
Mar 3, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·P NenoffH Schöfer
Jul 6, 2014·PLoS Neglected Tropical Diseases·Wendy W J van de SandeEd E Zijlstra
Oct 22, 2016·Mycoses·Olga C RojasGloria M González
Nov 1, 2016·PLoS Neglected Tropical Diseases·Ali WadalAhmed Hassan Fahal
Jun 9, 2017·Journal of Clinical Microbiology·Mark FraserElizabeth M Johnson
Apr 15, 2016·Journal of Clinical Microbiology·Andrew M BormanElizabeth M Johnson
Jun 24, 2016·PLoS Neglected Tropical Diseases·Suleiman Hussein SuleimanAhmed Hassan Fahal
Jan 16, 2020·PLoS Neglected Tropical Diseases·Amir ArastehfarSarah A Ahmed
Apr 2, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·B NyuykongeW W J van de Sande
Mar 20, 2019·Mycopathologia·Ruojun WangRuoyu Li
Nov 19, 2013·PLoS Neglected Tropical Diseases·Wendy W J van de Sande
Jul 31, 2020·PLoS Neglected Tropical Diseases·Elhadi A AhmedSarah A Ahmed
Dec 17, 2020·PLoS Neglected Tropical Diseases·Wilson LimWendy Wj van de Sande
Oct 12, 2021·International Journal of Dermatology·Alice Cortes de Castro LimaMarilia Marufuji Ogawa