Phenotypic varieties of sperm pathology: Genetic abnormalities or environmental influences can result in different patterns of abnormal spermatozoa

Animal Reproduction Science
Hector E Chemes

Abstract

The present paper reviews in detail ultrastructural and molecular studies addressed to characterize different phenotypes of sperm pathology in sterile men. In each case ultrastructural, immunocytochemical, molecular and genetic information is provided to differentiate two main kinds of sperm pathologies: systematic phenotypes with known or suspected genetic origin and non-systematic ones, usually secondary to different pathologies of the male reproductive system. Special attention is paid to detailed ultrastructural features profusely illustrated with electron micrographs. Diagnostic and fertility prognostic values of these phenotypes are also discussed and, when possible, comparison with similar pathologies in mammals and birds are discussed.

Citations

Oct 28, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Se Jeong KimSang Woo Lyu
Feb 28, 2020·BioMed Research International·Hua NieWeibing Qin
May 12, 2020·Molecular Human Reproduction·Yi-Ru ShenPao-Lin Kuo
Nov 12, 2018·Journal of Assisted Reproduction and Genetics·David F Albertini
Jan 15, 2020·Oxidative Medicine and Cellular Longevity·Marco BiagiElena Moretti
Jan 30, 2020·Biology of Reproduction·Bingbing WuWei Li
Jan 17, 2021·Journal of Assisted Reproduction and Genetics·Marziyeh Mazaheri MoghaddamEbrahim Sakhinia
Nov 14, 2020·Best Practice & Research. Clinical Endocrinology & Metabolism·Julie BeuroisCharles Coutton
Apr 21, 2021·Journal of Assisted Reproduction and Genetics·Stephanie CheungGianpiero D Palermo

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