Phenoxybenzamine for benign prostatic obstruction. Review of 200 cases

Urology
M CaineA Shapiro

Abstract

Two hundred patients treated with phenoxybenzamine for benign prostatic obstruction were reviewed. In 171 of these patients the treatment was given to relieve symptoms in patients not requiring operation, or in patients in whom operation was postponed. Eighty per cent of these patients derived benefit from the treatment, most commonly for the obstructive symptoms (78.7 per cent) but almost as often for nocturia (76 per cent). The treatment was also found to be useful in aiding catheter removal after an attack of acute retention, and in preventing recurrent attacks of acute retention. Side effects occurred in 30 per cent of patients, but necessitated cessation of treatment in only 10 per cent. They consisted of other alpha-blocking effects, and caused after stopping or reducing treatment.

References

Oct 1, 1977·The British Journal of Surgery·P F BorehamH Pearson

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Citations

Jan 1, 1994·Neurourology and Urodynamics·D M Gleason, M R Bottaccini
May 15, 2010·Current Urology Reports·Zuhair K Al-Hussaini, Kevin T McVary
Jan 2, 1985·European Journal of Pharmacology·J P HiebleE Zalaznik
Jan 1, 1982·Journal of Psychoactive Drugs·J Buffum
Jun 1, 1990·Ohio Medicine : Journal of the Ohio State Medical Association·D Stewart
Mar 1, 1995·British Journal of Urology·M Caine
Apr 24, 1982·British Medical Journal·A Savage
Jul 1, 1988·The Journal of Diabetic Complications·S A Kaplan, J G Blaivas
Feb 3, 2005·British Journal of Pharmacology·Thomas Taylor-ClarkJohn Foreman
Jan 1, 1993·Urology·J M Hernandez-Graulau
Jan 5, 2001·Expert Opinion on Investigational Drugs·C Forray, S A Noble
Jan 1, 1989·Scandinavian Journal of Urology and Nephrology·H Hedlund, K E Andersson
Aug 1, 1987·British Journal of Urology·R S KirbyE J Milroy
Jun 11, 1998·Mayo Clinic Proceedings·M M Lieber
Aug 1, 1984·The British Journal of Surgery·A G Tulloch
Jul 1, 1988·Medical Toxicology and Adverse Drug Experience·D E McWaine, W R Procci
Apr 1, 2002·The Physician and Sportsmedicine·Michael J Wehle, Scott W Lisson
Jun 1, 1991·Postgraduate Medicine·H D Itskovitz
Aug 1, 1983·The Journal of Urology·H HedlundA Ek
Jan 1, 1994·Pharmacology & Therapeutics·R R Ruffolo, J P Hieble
Sep 30, 1999·The Medical Clinics of North America·J J MedinaR G Moore
Nov 28, 2009·The Urologic Clinics of North America·Gregory B AuffenbergKevin T McVary

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