PMID: 8585105Oct 1, 1995Paper

Phenytoin as a risk factor in gingival hyperplasia

Therapeutic Drug Monitoring
F PerlíkV Patzelová

Abstract

Fifty-four out-patients with epilepsy who had been taking phenytoin for more than one year were examined for gingival hyperplasia. Approximately 76% of patients showed either mild or no gingival hyperplasia. Lesion severity was then compared statistically to phenytoin dosage and drug concentrations as well as to other clinical and laboratory parameters. There was a tendency for gingival hypertrophy to be associated with both increasing dosage of phenytoin per unit of body weight and the duration of phenytoin administration. All patients followed had a statistically significant progressive trend to increasing gingival hyperplasia with higher total and free phenytoin concentration.

Citations

Mar 12, 2005·Journal of the American Academy of Dermatology·Pooja KheraJoseph C English
Oct 9, 2001·European Journal of Clinical Investigation·L BrunetC Mendieta
Jun 11, 2008·Head & Face Medicine·Tareq Abu Saleh, Lawrence Stephen
Mar 31, 2015·International Journal of Molecular Medicine·Tamilselvan SubramaniParasuraman Padmanabhan
Jul 21, 2010·Journal of Clinical Periodontology·Gaganpreet KaurMiriam C J M Sturkenboom
Jun 10, 2011·Acta Neurologica Scandinavica·R Arya, S Gulati
May 22, 2013·Mediators of Inflammation·Tamilselvan SubramaniNoorjahan Banu Alitheen
Feb 7, 2001·Arquivos de neuro-psiquiatria·P C Trevisol-BittencourtA R Troiano
Feb 12, 2005·Journal of Child Neurology·Hüseyin TanIlhan Metin Dağsuyu
Dec 29, 2020·Journal of Periodontal Research·Claudio GalloCarla Mucignat-Caretta
Jun 13, 2015·The Journal of Contemporary Dental Practice·Yousef A AlJehani
May 31, 2021·Seizure : the Journal of the British Epilepsy Association·Ali A Asadi-PooyaNafiseh Mirzaei Damabi

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