PMID: 42512Apr 1, 1979

Pheochromocytoma--recognition and management

Current Problems in Cardiology
C V Ram, K Engelman

Abstract

Pheochromocytoma is an infrequent cause of hypertension. In spite of its rarity, pheochromocytoma has assumed notorious importance because or a wide variety of clinical features associated with this syndrome. Hypertension remains the most important clinical lead. The presence of other features, such as severe headache, perspiration, palpitations or orthostatic hypotension, makes the diagnosis of pheochromocytoma likely. The diagnosis of this condition can be made with greater certainty than that of any other form of secondary hypertension. Pharmacologic tests are no longer used for evaluation purposes. Biochemical tests are the most important aids to diagnosis, provided highly specific methods are used to determine the levels of urinary catecholamines or their metabolites. Interference by various drugs should be avoided. Most of the pheochromocytomas are found in the abdomen, predominantly in the adrenals. Successful outcome of surgery depends critically on adequate preoperative preparation of the patient with adrenergic blocking drugs and proper intraoperative care. Surgery should only be performed in an institution with experience in treating these tumors. Invasive localizing procedures could be dangerous in patients with phe...Continue Reading

Citations

Dec 1, 1989·Journal of the American College of Cardiology·G L Bakris, E D Frohlich
Jun 14, 2008·Headache·So-Hyang Im, Nam-Hee Kim
Sep 1, 1989·Progress in Cardiovascular Diseases·M C Houston
Nov 27, 2014·São Paulo Medical Journal = Revista Paulista De Medicina·You Jin HanHark Rim
Aug 26, 2006·Nature Clinical Practice. Nephrology·Joshua Fessel, David Robertson

Related Concepts

Adrenal Cancer
Adrenergic beta-Antagonists
Malignant Neoplasm of Urinary Bladder
Catecholamines
Differential Diagnosis
Hypertensive Disease
Pheochromocytoma, Extra-Adrenal
Pregnancy Complications

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