[Pheochromocytomas and paragangliomas in pregnancy: About four cases and key messages on management].

Gynécologie, Obstétrique, Fertilité & Sénologie
C DuquesnayC Garabedian

Abstract

The diagnosis of a pheochromocytoma or paraganglioma secreting during pregnancy is a rare and serious situation, involving maternal-fetal prognosis. The purpose of this case series is to discuss the management of these patients. This is a retrospective study of cases of pheochromocytoma (n=2) or paraganglioma (n=2) managed during pregnancy between 2013 and 2020 in one center (Lille, France). We report four cases of patients with a diagnosis of pheochromocytoma or paraganglioma during pregnancy, at respectively 4, 28, 31 and 34 weeks of amenorrhea (AS). Their pregnancies were affected by a sudden onset of hypertension sometimes associated with headaches, sweating, and palpitations. All patients delivered by Caesarean section after calcium channel blocker impregnation, with a good outcome. Tumor removal took place at a distance from delivery for each patient. The therapeutic strategy includes antihypertensive treatment with calcium channel blockers or alphablockers and surgical curative treatment linked to gestational age. Multidisciplinary management as well as early diagnosis can improve the maternal-fetal prognosis. The preferred way of delivery is Caesarean section, but vaginal delivery can also be considered. Removal should ...Continue Reading

References

Jan 8, 1999·World Journal of Surgery·J L HarringtonK D Ramin
Jul 5, 2002·World Journal of Surgery·Frits J BerendsH Jaap Bonjer
May 29, 2004·Anesthesiology·Stephanie C AplinMichael J Cole
Nov 30, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Laurence AmarAnne-Paule Gimenez-Roqueplo
Aug 17, 2006·Internal Medicine Journal·S GrodskiS Banting
Sep 6, 2011·European Journal of Endocrinology·Jacques W M Lenders
Mar 27, 2013·Journal of Forensic Sciences·Isabelle PluDominique Lecomte
Apr 18, 2013·Singapore Medical Journal·Jessie Wai Leng PhoonHong Liang Chua
Apr 17, 2014·BMJ : British Medical Journal·Kate BramhamLucy C Chappell
Jun 4, 2014·The Journal of Clinical Endocrinology and Metabolism·Jacques W M LendersWilliam F Young
Jun 18, 2015·The Journal of Clinical Endocrinology and Metabolism·Laurie A WingMarianne S Elston
Apr 7, 2017·European Journal of Endocrinology·K van der WeerdR A Feelders
Jul 28, 2019·Endocrinology and Metabolism Clinics of North America·Jacques W M LendersGraeme Eisenhofer
Nov 30, 2020·The Lancet. Diabetes & Endocrinology·Irina BancosUNKNOWN International Pheochromocytoma and Pregnancy Study Group
Dec 21, 2020·BJOG : an International Journal of Obstetrics and Gynaecology·K LangtonJwm Lenders

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Seminars in Pediatric Surgery
James K Moon, Peter Mattei
The New England Journal of Medicine
Benjamin C WhitelawJulia K Prague
Cancer Treatment and Research
Goswin Y Meyer-Rochow, Stan B Sidhu
The New England Journal of Medicine
Francesco Tassone
The New England Journal of Medicine
Hartmut P H NeumannCharis Eng
© 2021 Meta ULC. All rights reserved