Pheromone-inducible conjugation in Enterococcus faecalis: a model for the evolution of biological complexity?

International Journal of Medical Microbiology : IJMM
Briana K KozlowiczG M Dunny

Abstract

Pheromone-inducible transfer of the plasmid pCF10 in Enterococcus faecalis is regulated using a complicated network of proteins and RNAs. The plasmid itself has been assembled from parts garnered from a variety of sources, and many aspects of the system resemble a biological kluge. Recently several new functions of various pCF10 gene products that participate in regulation of plasmid transfer have been identified. The results indicate that selective pressures controlling the evolution of the plasmid have produced a highly complex regulatory network with multiple biological functions that may serve well as a model for the evolution of biological complexity.

References

Jun 10, 1977·Science·F Jacob
Oct 26, 1990·Science·R B Lobell, R F Schleif
May 9, 2003·Nature·Richard E LenskiChristoph Adami
Oct 15, 2005·Proceedings of the National Academy of Sciences of the United States of America·Josephine R ChandlerGary M Dunny
Dec 13, 2005·Proceedings of the National Academy of Sciences of the United States of America·Ke ShiCathleen A Earhart

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Citations

May 27, 2010·Applied Microbiology and Biotechnology·Jorge Rocha-EstradaMayra de la Torre
Dec 7, 2010·The Journal of Antimicrobial Chemotherapy·Guido WernerArnfinn Sundsfjord
Jul 6, 2007·PloS One·Shonna M McBrideMichael S Gilmore
Sep 25, 2008·Future Microbiology·Guido WernerWolfgang Witte
Dec 14, 2011·Applied Microbiology and Biotechnology·Jorge RochaMayra de la Torre
Sep 4, 2009·Trends in Microbiology·Antoni P A HendrickxWillem van Schaik
Nov 26, 2008·Endocrinology and Metabolism Clinics of North America·William W L HsiaoJesse Roth
May 30, 2008·FEMS Microbiology Ecology·Frances R SlaterSarah L Turner
Feb 24, 2006·International Journal of Medical Microbiology : IJMM·Paul Williams
Jun 3, 2014·The Journal of Physiology·James A Shapiro
Mar 30, 2016·Journal of Bacteriology·Gary M Dunny, Ronnie Per-Arne Berntsson
Oct 28, 2016·Molecular Microbiology·Minny BhattyPeter J Christie
Sep 19, 2019·Antimicrobial Agents and Chemotherapy·Marinelle RodriguesBreck A Duerkop
Feb 12, 2020·Science Advances·Jonathan H BethkeLingchong You
Jun 25, 2015·Microbiology Spectrum·Val Fernández LanzaTeresa M Coque

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