Philinopsides E and F, two new sulfated triterpene glycosides from the sea cucumber Pentacta quadrangularis

Natural Product Research
Shi-Long ZhangPeng Sun

Abstract

Two new sulfated triterpene glycosides, philinopside E (1) and F (2), have been isolated from the sea cucumber Pentacta quadrangularis. Their structures have been established by extensive spectral analysis (NMR and MS) and chemical evidence. Glycoside 1 showed significant cytotoxicity (Ed(50) 0.75-3.50 microg mL(-1)) against ten tumor cell lines.

References

Jul 4, 1990·Journal of the National Cancer Institute·P SkehanM R Boyd

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Citations

May 14, 2014·Marine Drugs·Yadollah BahramiChris Franco
Aug 15, 2008·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Alejandro M S Mayer, Kirk R Gustafson
Mar 11, 2015·Marine Drugs·Dmitry L AmininVladimir I Kalinin
Oct 19, 2017·Marine Drugs·Muhammad Abdul Mojid MondolMohamad Tofazzal Islam
Sep 19, 2017·Investigational New Drugs·Teresa Liliana Wargasetia, Widodo
Feb 6, 2008·Natural Product Reports·John W BluntMichèle R Prinsep
Jul 30, 2008·Natural Product Reports·Joseph D Connolly, Robert A Hill
Jan 30, 2009·Natural Product Reports·John W BluntMichèle R Prinsep
May 5, 2018·International Journal of Molecular Sciences·Yuri Khotimchenko
Nov 2, 2020·Developmental and Comparative Immunology·Ming Guo, Chenghua Li

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Methods Mentioned

BETA
column chromatography
NMR

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