PMID: 6539680Jan 1, 1984Paper

Phosphagens and glycogen content in skeletal muscle after treadmill training in young and old rats

European Journal of Applied Physiology and Occupational Physiology
C Bastien, J Sanchez

Abstract

The concentration of creatine phosphate (CrP), ATP, ADP, AMP and glycogen were measured in extensor digitorum longus (EDL) and in quadriceps muscles of 3, 6, 24, and 27 months old male Wistar rats groups. Young (3 months) and old (24 months) rats were trained for 12 weeks, 3 days a week, with running exercise session. Each training session was of 2 h. In sedentary groups and for both muscles, CrP, ATP, ADP, and glycogen contents decrease with aging (between 6 and 27 months). In spite of an AMP increase, total adenosine nucleotides (TAN) decrease significantly between 6-27 months (P less than 0.01) from 6.11 to 5.11 (EDL) and from 5.59 to 4.65 (quadriceps) mumol X g-1 wet weight muscle. After 12 weeks of physical training, the mean values of CrP, TAN, and glycogen were improved in both young and old rat groups. Moreover, the ATP/ADP ratios and the energy charge of the adenylate system were unrelated to age, but training decreases significantly the mean value of energy charge in both young and old groups. These results suggest that, as far as energy-rich phosphagen metabolism is concerned young and old muscles show the same pattern response to training.

References

Jan 1, 1976·Annual Review of Physiology·J O Holloszy, F W Booth
Jan 1, 1982·European Journal of Applied Physiology and Occupational Physiology·A N Belcastro, H Wenger
Oct 1, 1980·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·A N BelcastroA Bonen
Jan 1, 1983·European Journal of Applied Physiology and Occupational Physiology·J SanchezH Monod
Jun 1, 1980·Clinical Science·P MöllerK Hellström

❮ Previous
Next ❯

Citations

Sep 1, 1988·Pflügers Archiv : European journal of physiology·S SavageG A Brooks
Jun 1, 1989·Mechanisms of Ageing and Development·T JullienJ Verdetti
Jun 1, 1992·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·P Uhrín, T Liptaj
Sep 26, 2008·Exercise and Sport Sciences Reviews·Scott E GordonDavid M Thomson
Aug 8, 2013·Aging Cell·Gilles GouspillouPhilippe Diolez
Jul 19, 2005·Experimental Gerontology·Wim DeravePeter Hespel
May 1, 1986·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·W Leyko, G Bartosz
Dec 28, 2019·International Journal of Molecular Sciences·Spencer G MillerJeffrey J Brault

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.