Phosphate sugar isomerases and their potential for rare sugar bioconversion.

The Journal of Microbiology
Soo-Jung KimSoo-Jin Yeom


Phosphate sugar isomerases, catalyzing the isomerization between ketopentose/ketohexose phosphate and aldopentose/aldohexose phosphate, play an important role in microbial sugar metabolism. They are present in a wide range of microorganisms. They have attracted increasing research interest because of their broad substrate specificity and great potential in the enzymatic production of various rare sugars. Here, the enzymatic properties of various phosphate sugar isomerases are reviewed in terms of their substrate specificities and their applications in the production of valuable rare sugars because of their functions such as low-calorie sweeteners, bulking agents, and pharmaceutical precursor. Specifically, we focused on the industrial applications of D-ribose-5-phosphate isomerase and D-mannose-6-phosphate isomerase to produce D-allose and L-ribose, respectively.


Nov 1, 1995·The American Journal of Clinical Nutrition·G V LevinJ R Beadle
Jun 1, 1996·The Journal of Nutrition·G Livesey, J C Brown
Dec 1, 1996·Glycobiology·S MuniruzzamanA D Elbein
May 25, 2002·Journal of Nutritional Science and Vitaminology·Tatsuhiro MatsuoKen Izumori
Jun 5, 2002·Chemical & Pharmaceutical Bulletin·Masao AkagiHidehito Urata
Jul 6, 2002·Organic Letters·Hideyo TakahashiShiro Ikegami
Jan 4, 2003·Journal of Medicinal Food·Gilbert V Levin
Jul 6, 2004·Journal of Hepato-biliary-pancreatic Surgery·Mohammad Akram HossainHajime Maeta
Oct 20, 2005·Journal of Bioscience and Bioengineering·Akiko MurataMasaaki Tokuda
Feb 8, 2006·Applied and Environmental Microbiology·Hye-Jung KimDeok Kun Oh
Nov 6, 2008·Journal of Biotechnology·Ran-Young YoonDeok Kun Oh
Jan 23, 2009·Applied Microbiology and Biotechnology·Ran-Young YoonDeok Kun Oh
Sep 9, 2010·Journal of Agricultural and Food Chemistry·Chia-Jui LinTsuei-Yun Fang
Dec 7, 2010·Applied Microbiology and Biotechnology·Soo Jin YeomDeok Kun Oh
Jun 10, 2011·Applied Microbiology and Biotechnology·Yu-Ri Lim, Deok Kun Oh
Jul 19, 2011·Journal of Agricultural and Food Chemistry·Chia-Jui LinTsuei-Yun Fang
Feb 22, 2012·Journal of Industrial Microbiology & Biotechnology·Koen BeerensWim Soetaert
Feb 16, 2016·Applied Microbiology and Biotechnology·Wei XuWanmeng Mu
Feb 29, 2016·Applied Biochemistry and Biotechnology·Manisha J PatelDarshan H Patel

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