Phosphatidyl choline: Donor of 18-carbon unsaturated fatty acids for glycerolipid biosynthesis.

Lipids
P G Roughan

Abstract

Kinetics of radiocarbon inforporation into the phyosphatidyl choline of pumpkin leaf fed 1(-14)C-acetate at low light intensity were strongly suggestive of lipid bound fatty acids acting as substrates for desaturase enzymes. After pulse labeling in direct sunlight with the same precursor, phosphatidyl choline and phosphatidyl glycerol contained up to 90% of total glycerolipid radiocarbon at the shortest sampling times. Subsequent loss of radiocarbon from phyosphatidyl choline and a corresponding gain in other glycerolipids is taken to indicate a net flow of long chain fatty acids through phosphatidyl choline and into other lipids. It is proposed that there may be 2 separate synthetases in leaf tissue, one producing oleic and the other palmitic acids as their end products. Oleic acid is transferred almost exclusively to phosphatidyl choline where it is further desaturated to linoleic and linolenic acids before being made available for the biosynthesis of other lipids. Palmitic acid is transferred mainly to phosphatidyl glycerol, where it is desaturated to trans-delta3-hexadecenoic acid.

References

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Citations

Feb 3, 2007·Lipids·Shiu-Cheung Lung, Randall J Weselake
Jan 1, 1978·Progress in Biophysics and Molecular Biology·P J Quinn, W P Williams
Jan 1, 1981·Progress in Biophysics and Molecular Biology·P J Quinn
Jan 1, 1979·Progress in Lipid Research·J L Harwood
Nov 25, 1997·Biochimica Et Biophysica Acta·N Murata, Y Tasaka
Jul 1, 1977·Plant Physiology·R E Wilkinson, A E Smith
Sep 1, 1981·Plant Physiology·D J Murphy, R M Leech
Nov 1, 1979·European Journal of Biochemistry·H P SiebertzR Douce
Mar 24, 2016·Biochimica Et Biophysica Acta·Doug K Allen
Dec 1, 1987·Archives of Biochemistry and Biophysics·P G RoughanS H Cho
Jan 15, 1978·Archives of Biochemistry and Biophysics·C J BedordB Adams

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