Sep 10, 1971

Phosphatidylserine: selective enhancer of histamine release

Science
A GothM Knoohuizen

Abstract

Phosphatidylserine, in contrast with other phospholipids, markedly enhanced histamine release from rat peritoneal mast cells induced by dextran or protein antigens. This enhancing effect was selective for dextran and protein antigens and did not extend to the action of compound 48/80 or chymotrypsin. These findings suggest a role for phosphatidylserine in the response of mast cells to antigens.

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Mentioned in this Paper

Phosphatidylinositols
Mast Cell
Phosphatidylserines
Gene Products, Protein
Avazyme
Phosphatidylcholines
Antigens
phosphatidylserine
Peritoneum
Visceral Peritoneum

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