Phosphine free Mn-complex catalysed dehydrogenative C-C and C-heteroatom bond formation: a sustainable approach to synthesize quinoxaline, pyrazine, benzothiazole and quinoline derivatives

Chemical Communications : Chem Comm
Kalicharan DasDipankar Srimani

Abstract

Herein the first sustainable synthesis of quinoxalines, pyrazines and benzothiazoles catalysed by a phosphine free Mn(i) complex via acceptorless dehydrogenative coupling (ADC) is reported. This method is also applied successfully to synthesize quinolines via the dehydrogenation (removal of H2) and condensation (removal of H2O) reaction between 2-aminobenzyl alcohols and secondary alcohols.

References

Aug 11, 2007·Science·Chidambaram GunanathanDavid Milstein
Oct 11, 2007·Chemical Reviews·Aurore Loudet, Kevin Burgess
Jul 12, 2011·Accounts of Chemical Research·Chidambaram Gunanathan, David Milstein
Nov 28, 2012·Angewandte Chemie·Min ZhangMatthias Beller
Jan 25, 2013·Nature Chemistry·Stefan Michlik, Rhett Kempe
Jun 6, 2013·Angewandte Chemie·Stefan Michlik, Rhett Kempe
Jul 12, 2013·Journal of the American Chemical Society·Min ZhangMatthias Beller
Jan 25, 2014·Chemistry : a European Journal·Miguel Peña-LópezMatthias Beller
Nov 15, 2014·Chemical Reviews·Chidambaram Gunanathan, David Milstein
Aug 14, 2015·Angewandte Chemie·Avanashiappan NandakumarEkambaram Balaraman
Sep 29, 2015·Journal of the American Chemical Society·Nicklas DeiblRhett Kempe
Dec 24, 2015·Organic Letters·Seung Hyo Kim, Soon Hyeok Hong
Oct 7, 2016·Nature Communications·Saravanakumar ElangovanMatthias Beller
Dec 10, 2016·Journal of the American Chemical Society·Matthias MastalirKarl Kirchner
Jan 13, 2017·Angewandte Chemie·Nicklas Deibl, Rhett Kempe
Apr 21, 2017·Angewandte Chemie·Magnus B WidegrenMatthew L Clarke
May 17, 2017·Angewandte Chemie·Fabian KallmeierRhett Kempe
Jun 20, 2017·Journal of the American Chemical Society·Matthias MastalirKarl Kirchner
Aug 10, 2017·Journal of the American Chemical Society·Subrata ChakrabortyDavid Milstein
Aug 11, 2017·Journal of the American Chemical Society·Noel Angel Espinosa-JalapaDavid Milstein
Aug 19, 2017·Journal of the American Chemical Society·Shaomin FuQiang Liu
May 3, 2018·Nature Communications·Daniel ForbergRhett Kempe

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Citations

Mar 7, 2020·Organic & Biomolecular Chemistry·Bhaskar PaulSabuj Kundu
Nov 13, 2020·Molecular Diversity·Ayushi SethiyaShikha Agarwal
Jul 29, 2021·Biomaterials Science·Ahmad Reza BagheriJianbo Jia
Aug 10, 2021·Chemical Communications : Chem Comm·Kuhali DasBiplab Maji
Apr 16, 2019·The Journal of Organic Chemistry·Sertaç GençDerya Gülcemal
Jan 7, 2020·The Journal of Organic Chemistry·Moseen A ShaikhBoopathy Gnanaprakasam
Jan 21, 2020·The Journal of Organic Chemistry·Sk Sheriff ShahN D Pradeep Singh
Dec 17, 2020·The Journal of Organic Chemistry·Jiajun Wu, Christophe Darcel
Sep 7, 2021·Chemical Communications : Chem Comm·Sourajit BeraDebasis Banerjee
Sep 17, 2021·The Journal of Organic Chemistry·Rakesh MondalNanda D Paul
Sep 21, 2021·Chemical Communications : Chem Comm·Avijit MondalDipankar Srimani
Oct 1, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Yaqi ZhaoMing Lei
Nov 5, 2021·Chemical Communications : Chem Comm·Xuelu HeAiguo Wu
Feb 3, 2022·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Wenxin WangJinsong Peng

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