Phosphoglucose isomerases of hagfish, zebrafish, gray mullet, toad, and snake, with reference to the evolution of the genes in vertebrates

Molecular Biology and Evolution
Hsiao-wei Kao, Sin-Che Lee

Abstract

Phosphoglucose isomerase (PGI) is a protein with multiple functions. To infer its structure changes and evolution in vertebrates, we cloned cDNAs encoding PGI genes from hagfish (Paramyxine yangi), gray mullet (Mugil cephalus), zebrafish (Danio rerio), toad (Bufo melanosticus), and snake (Boiga kraepelini). Only one PGI gene was cloned in each of hagfish, toad, and snake, but two PGI genes were found in zebrafish and gray mullet, respectively. The PGI of hagfish encodes 554 amino acids, in contrast to the PGIs of bonyfishes, toad, and snake which encode 553 amino acids and the PGIs of mammals which encode 558 amino acids. Among 558 aligned amino acid sites, there are 314 sites (56.27%) totally conserved. To see if diversifying selection acts on PGI amino acids of vertebrates, we calculated the pairwise ratio of nonsynonymous versus synonymous substitution per site (Ka/Ks) and the ratio of radical amino acid changes versus conservative amino acid changes per sites (dR/dC) between PGI sequences. The average pairwise ratio between nonsynonymous substitutions per nucleotide (Ka) and synonymous substitutions per nucleotide (Ks) among vertebrate PGI sequences equals 0.047 +/- 0.019. The average pairwise ratio between radical amino ac...Continue Reading

References

Jan 1, 1990·Methods in Enzymology·J Hein
May 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·L A LiottaE Schiffmann
Dec 1, 1994·Molecular Phylogenetics and Evolution·A L Hughes
Mar 1, 1993·Journal of Molecular Evolution·A L Hughes, M K Hughes
Jan 1, 1996·Nucleic Acids Research·A BairochK Hofmann
Feb 1, 1996·Developmental Biology·P W Holland, J Garcia-Fernàndez
Jan 1, 1997·Nucleic Acids Research·A BairochK Hofmann
May 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·J ZhangM Nei
Dec 29, 1998·Molecular Biology and Evolution·Z YangM Hasegawa
May 13, 1999·Proceedings of the National Academy of Sciences of the United States of America·Y J SunC D Hsiao
Jul 27, 1999·Current Biology : CB·L D Hurst, N G Smith
Feb 10, 2000·Molecular Biology and Evolution·Z Yang, R Nielsen
Jun 2, 2000·Biochemical and Biophysical Research Communications·M J CaoT Ishihara
Sep 6, 2000·Trends in Biochemical Sciences·B Kisters-WoikeB Müller-Hill
Nov 10, 2000·Science·M Lynch, J S Conery
Jan 4, 2001·Journal of Molecular Evolution·A L Hughes
May 29, 2002·Molecular Biology and Evolution·Ziheng Yang, Rasmus Nielsen

❮ Previous
Next ❯

Citations

Apr 3, 2007·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Divya MathurLalit C Garg
Jun 15, 2011·BMC Evolutionary Biology·Mikhail L KuravskyVladimir I Muronetz
Jan 27, 2009·Gene Expression Patterns : GEP·Wen-Wen LinHsiao-Wei Kao
Oct 7, 2008·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Saren Gaowa, Shicui Zhang
Mar 17, 2017·International Journal of Molecular Sciences·Bo-Wen ZhaoZe-Xia Gao
Sep 16, 2005·Molecular Biology and Evolution·Karen D CrowGünter P Wagner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.