Phospholipids of the sea anemone: Quantitative distribution; absence of carbon-phosphorus linkages in glycerol phospholipids; structural elucidation of ceramide aminoethylphosphonate

Lipids
G Simon, G Rouser

Abstract

The phospholipid composition of the sea anemone (Anthopleura elegantissima) was determined by quantitative thin-layer chromatography (TLC). Phosphonic acids were not detected in phosphatidyl choline, phosphatidyl ethanolamine, or phosphatidyl serine following isolation and hydrolysis. The structure of ceramide aminoethylphosphonate, a phosphonolipid, was elucidated by hydrolysis and oxidative degradation followed by characterization of the products by TLC and gas-liquid chromatography. The long-chain base was shown to be sphingosine with the 2-aminoethylphosphonic acid group attached through the primary hydroxyl group at carbon one. Ceramide aminoethylphosphonate is therefore 1-(O-phosphonoethylamine)-N-acyl sphingosine.

References

Jan 1, 1957·The Biochemical Journal·M V RAJAGOPAL, K SOHONIE
Mar 1, 1962·Comparative Biochemistry and Physiology·M G HACKM E LOWE
Apr 1, 1965·Journal of the American Oil Chemists' Society·R C GAVER, C C SWEELEY
Sep 19, 1959·Nature·M HORIGUCHI, M KANDATSU
Dec 31, 1949·Nature·C S HANES, F A ISHERWOOD

Citations

Oct 1, 1970·Chemistry and Physics of Lipids·K A Karlsson
Jan 1, 1982·Progress in Lipid Research·J D Joseph
Jan 1, 1984·Progress in Lipid Research·M C Moschidis
Jan 1, 1979·Die Nahrung·Y El-Shattory
Oct 27, 2015·Biochimica Et Biophysica Acta·Akiko Yamaji-HasegawaToshihide Kobayashi
Mar 1, 1992·Revue française de transfusion et d'hémobiologie : bulletin de la Société nationale de transfusion sanguine·Y PlanquesJ F Lacoste-Bourgeacq
Jun 5, 1970·Biochemical and Biophysical Research Communications·K A Karlsson
Jan 16, 2021·Biochemistry·Juan Palacios-OrtegaJ Peter Slotte
Feb 25, 1974·Biochimica Et Biophysica Acta·K A Karlsson, B E Samuelsson

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