PMID: 45526Jan 1, 1977

Phosphonoglycoprotein from Metridium senile--heterogeneity of glycoproteins containing aminoethylphosphonic acid

Comparative Biochemistry and Physiology. B, Comparative Biochemistry
J C HurleyS H Bishop

Abstract

1. After separation by SDS gel-chromatography, analysis of AEP-containing glycoproteins from M. senile, indicated 66% amino acids with 220 AEP res./1000 res. and 30% carbohydrate for high mol. wt (greater than 10(7) forms and 80% amino acids with 25-50 AEP res./1000 res. and 10% carbohydrate for low mol. wt (2-4 x 10(4) forms. 2. Uronic acids, sulfate, lipid, and sialic acids were absent. 3. Mild base digestion released AEP-hexosamine containing oligosaccharides and destroyed ser-thr residues in the high mol. wt components. 4. Phosphonoglycoproteins appear to be acidic connective tissue components with AEP linked to hexosamine containing oligosaccharide side chains.

Citations

Jan 15, 1975·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·S D Young
Aug 1, 1974·The Journal of Cell Biology·B Bowers, E D Korn
Feb 1, 1974·Canadian Journal of Biochemistry·K J StevensonG H Dixon
Feb 25, 1974·Biochimica Et Biophysica Acta·K A Karlsson, B E Samuelsson
Apr 4, 1969·Science·J S Kittredge, E Roberts
Feb 16, 1971·Biochimica Et Biophysica Acta·R L Katzman, R W Jeanloz
Jul 1, 1972·Archives of Biochemistry and Biophysics·M BalA G Datta
Jan 1, 1974·Annual Review of Microbiology·J E Gander
Feb 13, 1974·Journal of Chromatography·C Bucke
May 22, 1970·Science·K E Kennedy, G A Thompson
May 1, 1968·Comparative Biochemistry and Physiology·C R Liang, H Rosenberg
Apr 1, 1966·Analytical Biochemistry·R Gatt, E R Berman
Oct 1, 1962·Analytical Biochemistry·T BITTER, H M MUIR
Oct 1, 1963·Comparative Biochemistry and Physiology·L WARREN

Related Concepts

Aminoethylphosphonic Acid
Glycoproteins
Amino Acids, I.V. solution additive
Chromatography
Cnidaria
Sea Anemones
Uronic Acids
Neoglycoproteins
Sialic Acids
Digestion

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