PMID: 8588836Oct 1, 1995Paper

Phosphorylated and non-phosphorylated neurofilament proteins: distribution in the rat hippocampus and early changes after kainic acid induced seizures

Journal of Chemical Neuroanatomy
Q YangK G Haglid

Abstract

The regional distribution of neurofilament proteins in the rat hippocampus and their early changes after kainic acid induced seizures were investigated immunocytochemically with antibodies against light weight neurofilament, phosphorylated and non-phosphorylated heavy weight neurofilament. The light weight and non-phosphorylated heavy weight neurofilaments were distributed more unevenly than the phosphorylated neurofilament. The perikarya and processes of pyramidal cells in the CA3 field contained the highest light weight and non-phosphorylated heavy weight neurofilaments, while the perikarya of granule cells contained only few light weight neurofilament and the perikarya of CA1 pyramidal cells were even devoid of immunoreactivity of both light and heavy weight neurofilaments. The fiber staining of the light weight and non-phosphorylated heavy weight neurofilaments, especially the former, was less in the CA1 field and molecular layer of dentate gyrus. The phosphorylated neurofilament immunoreactivity was identified only in axons. Mossy fibers, the axons of granule cells, contained the light weight and phosphorylated heavy weight neurofilaments, but not the non-phosphorylated neurofilament. Seven days after the kainic acid induc...Continue Reading

References

Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·H TowbinJ Gordon
Nov 1, 1992·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·I J Llewellyn-Smith, J B Minson
Sep 3, 1990·Brain Research·P KlosenP van den Bosch de Aguilar
Jan 1, 1985·Anatomy and Embryology·S Davies, C Köhler
Nov 1, 1988·Journal of Neuropathology and Experimental Neurology·V ManettoP Gambetti
Jul 1, 1988·Trends in Neurosciences·A Matus
May 1, 1989·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·B M Riederer
Jan 1, 1985·Journal of Neurochemistry·J N WoodA J Dowding
Nov 1, 1987·Journal of Neurochemistry·J E KarlssonK G Haglid
Apr 1, 1988·Trends in Pharmacological Sciences·I Wessler
Jan 1, 1986·Experimental Cell Research·D Dahl, A Bignami
Jan 1, 1986·Journal of Neuroscience Research·D DahlA Bignami
Jan 1, 1986·Journal of Neuropathology and Experimental Neurology·L C CorkD L Price
Apr 1, 1986·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·G Shaw
Jun 1, 1985·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J Q TrojanowskiV M Lee
Sep 1, 1983·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·W F HickeyN K Gonatas
Apr 1, 1984·The Journal of Cell Biology·N HirokawaM B Willard
Sep 10, 1984·The Journal of Comparative Neurology·S N LawsonB H Anderton
May 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·M E GoldsteinN H Sternberger
Oct 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·L A Sternberger, N H Sternberger
Jan 1, 1984·Acta Neuropathologica·T Kirino, K Sano
Jul 15, 1980·The Journal of Comparative Neurology·J V NadlerC W Cotman
May 1, 1993·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Y KakuT Taniguchi
Apr 1, 1993·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·B M RiedererL I Binder

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Citations

May 24, 2005·Hormones and Behavior·Eugenia PapalexiEfthimia Kitraki
Dec 14, 2017·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Joan S BaizerSandra F Witelson
Nov 2, 2018·Scientific Reports·Daniel Z RadeckiAlexander Gow
Apr 9, 2020·International Journal of Molecular Sciences·Yam Nath PaudelMohd Farooq Shaikh

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