Phosphorylation of RACK1 in plants

Plant Signaling & Behavior
Jin-Gui Chen

Abstract

Receptor for Activated C Kinase 1 (RACK1) is a versatile scaffold protein that interacts with a large, diverse group of proteins to regulate various signaling cascades. RACK1 has been shown to regulate hormonal signaling, stress responses and multiple processes of growth and development in plants. However, little is known about the molecular mechanism underlying these regulations. Recently, it has been demonstrated that Arabidopsis RACK1 is phosphorylated by an atypical serine/threonine protein kinase, WITH NO LYSINE 8 (WNK8). Furthermore, RACK1 phosphorylation by WNK8 negatively regulates RACK1 function by influencing its protein stability. These findings promote a new regulatory system in which the action of RACK1 is controlled by phosphorylation and subsequent protein degradation.

References

Oct 26, 2002·Oncogene·Betty Y ChangChristine A Cartwright
Nov 19, 2002·Molecular Pharmacology·Angela McCahillStephen J Yarwood
Apr 12, 2005·Plant Molecular Biology·Patrick GiavaliscoPaola Fucini
Feb 7, 2006·Progress in Neurobiology·Ella H SklanHermona Soreq
Jul 11, 2006·Journal of Experimental Botany·Jin-Gui ChenAlan M Jones
Aug 22, 2008·Protein Science : a Publication of the Protein Society·Hemayet UllahLars Christian Pedersen
Aug 30, 2008·The Plant Cell·Ayako NakashimaKo Shimamoto
Oct 25, 2008·BMC Plant Biology·Jianjun Guo, Jin-Gui Chen
Jul 9, 2009·Journal of Experimental Botany·Jianjun GuoJin-Gui Chen
Jun 2, 2011·Plant Signaling & Behavior·Thanos Ghelis
Sep 29, 2011·Molecular Systems Biology·Karsten KlopffleischAlan M Jones
Oct 8, 2011·Cell Communication and Signaling : CCS·David R AdamsPatrick A Kiely
Aug 7, 2013·Cell Communication and Signaling : CCS·Dorit RonPatrick A Kiely
Aug 15, 2013·The Plant Journal : for Cell and Molecular Biology·Corinna SpethSascha Laubinger
Dec 19, 2013·Genes & Cancer·Valentina GandinZe'ev A Ronai
May 29, 2014·International Journal of Molecular Sciences·Baosheng WangQian Zhao
Jun 3, 2014·Oncogene·J-J Li, D Xie
Dec 10, 2014·Plant Physiology·Daisuke UranoJin-Gui Chen

❮ Previous
Next ❯

Citations

Sep 23, 2016·BioMed Research International·Xue ZhangGuotian Li

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.