Photo-activated CO-releasing molecules (PhotoCORMs) of robust sawhorse scaffolds [μ(2)-OOCR(1), η(1)-NH2CHR(2)(C = O] OCH3, Ru(I)2CO4

Dalton Transactions : an International Journal of Inorganic Chemistry
Shuhong YangWeiqiang Zhang

Abstract

A class of sawhorse-type ruthenium(i) complexes featuring a stable CORM sphere with diverse carboxylic and amino acid derivatives were synthesized and validated as lead structures for photo-activated CO-releasing molecules (PhotoCORMs). The CO release of these CORMs was triggered by 365 nm UV irradiation. Cell viability studies indicated that 3a and 3f were non-toxic both in the dark and in UV light, making them excellent lead structures for therapeutic CORMs.

References

Aug 19, 2003·Angewandte Chemie·Tony R JohnsonRoberto Motterlini
May 19, 2004·British Journal of Pharmacology·Roberta ForestiRoberto Motterlini
Apr 4, 2007·Dalton Transactions : an International Journal of Inorganic Chemistry·Tony R JohnsonRoberto Motterlini
Apr 20, 2007·Dalton Transactions : an International Journal of Inorganic Chemistry·Roger Alberto, Roberto Motterlini
Apr 2, 2008·Chemical Communications : Chem Comm·Johanna NieselUlrich Schatzschneider
Feb 26, 2009·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Frédéric SchmittLucienne Juillerat-Jeanneret
Aug 8, 2009·Dalton Transactions : an International Journal of Inorganic Chemistry·Hendrik PfeifferUlrich Schatzschneider
Dec 31, 2009·Inorganic Chemistry·R Dale RimmerPeter C Ford
Sep 3, 2010·Inorganic Chemistry·Wei-Qiang ZhangJason M Lynam
Sep 3, 2010·Nature Reviews. Drug Discovery·Roberto Motterlini, Leo E Otterbein
Dec 7, 2010·Journal of the American Chemical Society·Urara HasegawaJeffrey A Hubbell
Dec 8, 2010·Journal of Inorganic Biochemistry·Robert KretschmerMatthias Westerhausen
Jan 6, 2011·Journal of the American Chemical Society·Teresa Santos-SilvaMaria J Romão
Mar 16, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Sian H CrookRoberto Motterlini
Jul 16, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Lindsay HewisonRoberto Motterlini
Sep 2, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Fabio ZobiAnna Yu Bogdanova
Dec 14, 2011·Inorganic Chemistry·Margarita A GonzalezPradip K Mascharak
Feb 22, 2012·Chemical Society Reviews·Carlos C RomãoGonçalo J L Bernardes
Oct 20, 2012·Journal of the American Chemical Society·Agustin E PierriPeter C Ford
Dec 12, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·João D SeixasCarlos C Romão
Aug 10, 2013·Journal of Medicinal Chemistry·Fabio ZobiAnna Yu Bogdanova
Jan 28, 2014·European Journal of Medicinal Chemistry·Pengpeng WangQian Zheng
Jan 28, 2014·Chemical Communications : Chem Comm·Jean-Daniel CompainSylvie Chardon-Noblat
Mar 19, 2014·British Journal of Pharmacology·U Schatzschneider
Apr 26, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·Sandesh PaiUlrich Schatzschneider
Jul 30, 2014·Angewandte Chemie·Sandra García-Gallego, Gonçalo J L Bernardes
Nov 28, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·João D SeixasCarlos C Romão

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Citations

Jul 25, 2018·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Hidehiko Nakagawa
Jul 25, 2019·International Journal of Molecular Sciences·Muhammad FaizanZiwei Gao
Oct 15, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Nourhan M IbrahimAhmed M Mansour

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