PMID: 7528615Jul 1, 1994Paper

Photoablation of gelatin with the free-electron laser between 2.7 and 6.7 microns

Journal of Refractive and Corneal Surgery
B Jean, T Bende

Abstract

Photoablation in the infrared (IR) is an option for future refractive and corneal surgery; its basic principles have not yet been investigated systematically. For the first time, the free electron laser allows the dynamic study of photoablation over a wide range of wavelengths with variable combinations of pulselength and energy. The goal of this study is to use the free electron laser as a tool to describe photoablation in the IR quantitatively. We studied the function of wavelength as it is related to target material spectroscopy and the effects of corneal hydration and the pulse repetition rate. Surface absorption spectroscopy of the human cornea and of gelatin as a proven model of the cornea was performed between 2.7 and 6.7 microns. Gelatin probes of well-defined thickness (140 +/- 5 microns) and controlled hydration (wet/dry weight 1 to 4.5) served as target material. Photoablation was performed with the Vanderbilt University free electron laser (Nashville, Tenn) in September 1992 at a fluence of 1.27 J/cm2, and a macropulse of 4 microseconds, composed of 2 ps micropulses at a 2.9 GHz pulse repetition rate. Wavelength was tunable between 2.7 and 6.7 microns at stable beam profiles. Ablation experiments were performed as a...Continue Reading

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